Section 56
Chapter 55,183

Primary squamous cell carcinoma of the breast: A rare case report

Carbone, S.; Lobo Alvarez, R.; Lamacchia, A.; Almenar Gil, A.; Martin Hernandez, R.; Lopez Guerra, J.Luis.; Marsiglia, H.

Reports of Practical Oncology and Radiotherapy Journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology 17(6): 363-366


ISSN/ISBN: 1507-1367
PMID: 24377039
DOI: 10.1016/j.rpor.2012.07.004
Accession: 055182277

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Squamous cells are normally not found inside the breast. Therefore, a primary squamous cell carcinoma of the breast is an exceptional phenomenon and the management of this type of disease is still debated. Clinical outcome assessment of a patient with squamous cell carcinoma of the breast. We report a case of primary squamous cell carcinoma of the breast (T1cN0M0) in a 51-years-old woman who underwent breast conserving surgery plus adjuvant chemotherapy and radiation therapy (RT). With a follow up of 43 months, the patient is alive with no evidence of local or distant recurrence. The patient had Grade 2 acute skin toxicity. No late skin or respiratory toxicity was observed. Pure primary squamous cell carcinoma of the breast is a rare and aggressive disease, often treatment-refractory. Our case shows that the addition of RT after breast conserving surgery, allows to achieve a high local control without adding severe toxicity. A multidisciplinary approach seems to be the optimal management for early stages in this rare disease.

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