Primary squamous cell carcinoma of the breast: A rare case report
Carbone, S.; Lobo Alvarez, R.; Lamacchia, A.; Almenar Gil, A.; Martin Hernandez, R.; Lopez Guerra, J.Luis.; Marsiglia, H.
Reports of Practical Oncology and Radiotherapy Journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology 17(6): 363-366
2012
ISSN/ISBN: 1507-1367 PMID: 24377039 DOI: 10.1016/j.rpor.2012.07.004
Accession: 055182277
Squamous cells are normally not found inside the breast. Therefore, a primary squamous cell carcinoma of the breast is an exceptional phenomenon and the management of this type of disease is still debated. Clinical outcome assessment of a patient with squamous cell carcinoma of the breast. We report a case of primary squamous cell carcinoma of the breast (T1cN0M0) in a 51-years-old woman who underwent breast conserving surgery plus adjuvant chemotherapy and radiation therapy (RT). With a follow up of 43 months, the patient is alive with no evidence of local or distant recurrence. The patient had Grade 2 acute skin toxicity. No late skin or respiratory toxicity was observed. Pure primary squamous cell carcinoma of the breast is a rare and aggressive disease, often treatment-refractory. Our case shows that the addition of RT after breast conserving surgery, allows to achieve a high local control without adding severe toxicity. A multidisciplinary approach seems to be the optimal management for early stages in this rare disease.