+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Prophylactic treatment uptake and compliance with recommended follow up among HIV exposed infants: a retrospective study in Addis Ababa, Ethiopia

Prophylactic treatment uptake and compliance with recommended follow up among HIV exposed infants: a retrospective study in Addis Ababa, Ethiopia

Bmc Research Notes 4: 563

Children are being infected by HIV/AIDS mainly through mother-to-child transmission. In Ethiopia currently more than 135,000 children are living with HIV/AIDS. The aim of this study was to describe the pattern of ARV uptake after birth, co-trimoxazole prophylaxis and follow up compliance, and to examine which factors are associated with the intervention outcome. A retrospective quantitative study design was used for data collection through two hospitals. All infants who were delivered by HIV infected mothers between October 2008 and August 2009 were included and information regarding treatment adherence during their first 6 months of age was collected. 118 HIV exposed infant-mother pairs were included in the study. 107 (90.7%) infants received ARV prophylaxis at birth. Sixty six (56%) of the infants were found to be adherent to co-trimoxazole prophylactic treatment. The majority (n = 110(93.2%)) of infants were tested HIV negative with DNA/PCR HIV test at the age of sixth weeks. Infants who took ARV prophylaxis at birth were found to be more likely to adhere with co-trimoxazole treatment: [OR = 9.43(95% CI: 1.22, 72.9)]. Similarly, infants whose mothers had been enrolled for HIV/ART care in the same facility [OR = 14(95% CI: 2.6, 75.4)], and children whose fathers were tested and known to be HIV positive [OR = 3.0(95% CI: 1.0, 9.0)] were more likely to adhere than their counterparts. Infants feeding practice was also significantly associated with adherence χ2 -test, p < 0.01. The proportion of ARV uptake at birth among HIV exposed infants were found to be high compared to other similar settings. Mother-infant pair enrolment in the same facility and the infant's father being tested and knew their HIV result were major predictors of infants adhering to treatment and follow up. However, large numbers of infants were lost to follow up.

Please choose payment method:

(PDF emailed within 0-6 h: $19.90)

Accession: 055231947

Download citation: RISBibTeXText

PMID: 22201727

DOI: 10.1186/1756-0500-4-563

Related references

Major Risk Factors, Clinical and Laboratory Characteristics of Patients with Hepatocellular Carcinoma; a Retrospective Study at Tikur Anbassa Hospital, Addis Ababa University, Addis Ababa, Ethiopia. Ethiopian Medical Journal 53(3): 127-132, 2016

Uptake and performance of prevention of mother-to-child transmission and early infant diagnosis in pregnant HIV-infected women and their exposed infants at seven health centres in Addis Ababa, Ethiopia. Tropical Medicine and International Health 22(6): 765-775, 2017

Adherence to recommended lifestyle modifications and factors associated for hypertensive patients attending chronic follow-up units of selected public hospitals in Addis Ababa, Ethiopia. Patient Preference and Adherence 11: 323-330, 2017

Experience of uetropubic urethrolysis and sling operation for the treatment of post fistula repair residual incontinence at the Addis Ababa Fistula Hospital, Addis Ababa Ethiopia. Ethiopian Medical Journal 46(1): 29-35, 2008

The Growth and Management of Addis Ababa Visible and Invisible Actors in Urban Management and Emerging Trends of Informalization A Case Study from Kolfe-keranio Sub-City, Addis Ababa, Ethiopia. Norsk Geografisk Tidsskrift / Norwegian Journal of Geography 62(4): 306-306, 2008

Misdiagnosis of pulmonary tuberculosis and associated factors in peripheral laboratories: a retrospective study, Addis Ababa, Ethiopia. Bmc Research Notes 11(1): 291, 2018

Assessment of breast self-examination practice and its associated factors among female undergraduate students in Addis Ababa University, Addis Ababa, Ethiopia, 2016. Breast Cancer 11: 21-28, 2019

Prevalence of intestinal parasites, salmonella and shigella among apparently health food handlers of Addis Ababa University student's cafeteria, Addis Ababa, Ethiopia. Bmc Research Notes 8: 17, 2016

Patterns of Neural Tube Defects at two Teaching Hospitals in Addis Ababa, Ethiopia a Three Years Retrospective Study. Ethiopian Medical Journal 53(3): 119-126, 2016

Breast and cervical cancer patients' experience in Addis Ababa city, Ethiopia: a follow-up study protocol. Bmj Open 9(4): E027034, 2019

Evaluation of Ceftriaxone utilization in internal medicine wards of general hospitals in Addis Ababa, Ethiopia: a comparative retrospective study. Journal of Pharmaceutical Policy and Practice 8: 26, 2015

Patterns of lumbar myelographic findings in patients with LBP a 5 years retrospective study at Yehuleshet Higher Clinic, Addis Ababa, Ethiopia. Ethiopian Medical Journal 48(3): 229-236, 2010

Quality of anticoagulation management with warfarin among outpatients in a tertiary hospital in Addis Ababa, Ethiopia: a retrospective cross-sectional study. Bmc Health Services Research 17(1): 389, 2018

Non-compliance and associated factors against smoke-free legislation among health care staffs in governmental hospitals in Addis Ababa, Ethiopia: an observational cross-sectional study. Bmc Public Health 19(1): 91-91, 2019

Effect of antiretroviral therapy on changes in the fertility intentions of human immunodeficiency virus-positive women in Addis Ababa, Ethiopia: a prospective follow-up study. Epidemiology and Health 39: E2017028, 2017