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RAN translation: fragile X in the running

RAN translation: fragile X in the running

Neuron 78(3): 405-408

In this issue of Neuron, Todd et al. (2013) reveal that noncanonical repeat associated non-AUG (RAN) translation occurs on nonexpanded (CGG)30-50 and premutation (CGG)59-160 repeats, associated with the FMR1 gene, suggesting that the polyglycine and polyalanine products might have natural and pathogenic roles.

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Accession: 055333109

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PMID: 23664607

DOI: 10.1016/j.neuron.2013.04.034

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