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RANKL-based osteoclastogenic assays from murine bone marrow cells

RANKL-based osteoclastogenic assays from murine bone marrow cells

Methods in Molecular Biology 1130: 307-313

Osteoclasts are the only cell type in the body to resorb bone. Osteoclasts play a critical role in physiologic and pathologic bone remodeling. Many genetic mouse models affect the skeleton by regulating osteoclast function directly or indirectly. This protocol describes a procedure for generating osteoclasts from mouse bone marrow cells using macrophage colony stimulating factor and receptor activator of NF-κB ligand.

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Accession: 055333202

Download citation: RISBibTeXText

PMID: 24482183

DOI: 10.1007/978-1-62703-989-5_23

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