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RAS's cloak of invincibility slips at last?



RAS's cloak of invincibility slips at last?



Cancer Cell 25(1): 5-6



KRAS is the most frequently activated oncogene in human cancer, but it has, so far, shrugged off all attempts to inhibit its function directly. However, a recent report provides an entirely new approach to blocking mutant KRAS with small molecules and has the added benefit of sparing the wild-type protein.

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Accession: 055333416

Download citation: RISBibTeXText

PMID: 24434204

DOI: 10.1016/j.ccr.2013.12.016



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