EurekaMag.com logo
+ Site Statistics
References:
53,623,987
Abstracts:
29,492,080
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on LinkedInFollow on LinkedIn

+ Translate

RDW as an additional marker in inflammatory bowel disease/undifferentiated colitis



RDW as an additional marker in inflammatory bowel disease/undifferentiated colitis



Digestive Diseases and Sciences 53(9): 2521-2523



Anemia is a common complication in inflammatory bowel disease patients. We postulate that the distribution of lesions in Crohn's disease is more likely than ulcerative colitis to lead to malabsorption as an additional cause of anemia. RDW, a simple and inexpensive test could be an additional differentiating test. Retrospective review of 284 cases of which 156 cases were diagnosed with Crohn's disease and 128 cases were diagnosed with ulcerative colitis. There was a significant difference in the mean RDW between the Crohn's and the ulcerative colitis cases (14.9 vs. 14.3, P = .027). We conclude there is a statistical significance between the two groups though this may not represent a clinically significant difference. From our analysis we conclude that RDW is statistically significant and with the implementation of a more rigorous study design and analysis of further data RDW may prove to be a clinically effective marker in differentiating Crohn's disease from ulcerative colitis.

(PDF emailed within 0-6 h: $19.90)

Accession: 055333999

Download citation: RISBibTeXText

PMID: 18259864

DOI: 10.1007/s10620-007-0176-8



Related references

De novo Crohn's Disease after Ileal Pouch-Anal Anastomosis for Ulcerative Colitis and Inflammatory Bowel Disease Unclassified: Long-Term Follow-Up of a Prospective Inflammatory Bowel Disease Registry. American Surgeon 82(10): 977-981, 2016

Identification of a new WASP and FKBP-like (WAFL) protein in inflammatory bowel disease: a potential marker gene for ulcerative colitis. International Journal of Colorectal Disease 23(10): 921-930, 2008

Morphological findings for differential diagnosis of chronic inflammatory bowel disease ulcerative colitis crohns disease indeterminate colitis. Internist 32(9): 511-517, 1991

Morphologic criteria applicable to biopsy specimens for effective distinction of inflammatory bowel disease from other forms of colitis and of Crohn's disease from ulcerative colitis. Scandinavian Journal of Gastroenterology 34(1): 55-67, 1999

Surgical treatment of inflammatory bowel disease of the colon. Ulcerative colitis and granulomatous (Crohn's) colitis. American Journal of Surgery 130(5): 528-531, 1975

Mucosal biopsy diagnosis of colitis: acute self-limited colitis and idiopathic inflammatory bowel disease. Gastroenterology 107(3): 755-763, 1994

A SPECIAL MEETING REVIEW EDITION: CCFA/Advances in Inflammatory Bowel Diseases 2015: Highlights in Ulcerative Colitis and Crohn's Disease: A Review of Selected Presentations From the CCFA/Advances in Inflammatory Bowel Diseases 2015 Clinical and Research Conference • December 10-12, 2015 • Orlando, FloridaSpecial Reporting on:• New and Future Adhesion Molecule-Based Therapies in IBD• Efficacy and Safety of Vedolizumab for Inflammatory Bowel Disease in Clinical Practice• A Multicen. Gastroenterology & Hepatology 12(2 Suppl 1): 1-20, 2016

Bowel-associated dermatosis - arthritis syndrome in a patient with ulcerative colitis: an extraintestinal manifestation of inflammatory bowel disease. Clinical Journal of Gastroenterology 7(5): 410-413, 2016

C-ANCA/proteinase 3-positive colitis in children: a distinctive form of inflammatory bowel disease or vasculitis with colitis as initial presentation?. Journal of Pediatric Gastroenterology and Nutrition 57(4): 489-492, 2014

Morphologic findings in differential diagnosis of chronic inflammatory bowel diseases (ulcerative colitis, Crohn disease, indeterminate colitis). Der Internist 32(9): 511-517, 1991

Bowel-associated dermatosis-arthritis syndrome during ulcerative colitis: A rare extra-intestinal sign of inflammatory bowel disease. Annales de Dermatologie et de Venereologie 143(5): 377-381, 2016

Faecal S100A12 as a non-invasive marker distinguishing inflammatory bowel disease from irritable bowel syndrome. Gut 56(12): 1706-1713, 2007

Non-steroidal anti-inflammatory drugs are associated with emergency admission to hospital for colitis due to inflammatory bowel disease. Gut 40(5): 619-622, 1997

RDW can be a useful additional marker in diagnosing Crohn's disease and ulcerative colitis. Digestive Diseases and Sciences 53(10): 2828-2829, 2008

Activin A: a novel player and inflammatory marker in inflammatory bowel disease?. Laboratory Investigation; A Journal of Technical Methods and Pathology 77(4): 311-318, 1997