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Radiation-induced dedifferentiated chondrosarcoma with orbital invasion

Radiation-induced dedifferentiated chondrosarcoma with orbital invasion

Ophthalmic Plastic and Reconstructive Surgery 30(3): 205-208

To report 2 interventional cases of dedifferentiated chondrosarcoma with orbital involvement after radiotherapy performed in childhood and to review the literature on chondrosarcoma in the orbit following radiation treatment. Retrospective analysis of medical records of 2 patients with chondrosarcoma of the orbits with review of the literature. The first patient developed chondrosarcoma of the orbital and maxillary sinus 36 years after external beam radiation therapy to the OS to treat retinoblastoma. The second patient developed a large orbital chondrosarcoma 35 years after external beam radiation therapy in the treatment of craniofacial fibrous dysplasia. These cases highlight the risk of secondary chondrosarcoma in patients following radiotherapy and the importance of lifetime monitoring.

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Accession: 055345149

Download citation: RISBibTeXText

PMID: 24807535

DOI: 10.1097/IOP.0000000000000168

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