+ Site Statistics
References:
54,258,434
Abstracts:
29,560,870
PMIDs:
28,072,757
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

Radiation-induced sarcoma in bronchial stump after thoracic radiation therapy for small-cell lung cancer



Radiation-induced sarcoma in bronchial stump after thoracic radiation therapy for small-cell lung cancer



Journal of Cancer Research and Therapeutics 7(2): 198-200



We report a rare case of radiation-induced sarcoma (RIS) that arose in the right bronchial stump, 8 years after right pneumonectomy followed by adjuvant chemotherapy and thoracic radiotherapy for a localized small-cell lung cancer. The patient was treated in 2002 with 6 MV X-ray irradiation in a total dose of 60 Gy. Eight years after the end of radiotherapy, he presented with an undifferentiated high-grade pleomorphic sarcoma. Although an increased rate of soft tissue sarcoma has been reported after radiotherapy for some solid cancers or lymphomas, to our knowledge, this is the first report of RIS related to small-cell lung cancer.

(PDF emailed within 0-6 h: $19.90)

Accession: 055345342

Download citation: RISBibTeXText

PMID: 21768713

DOI: 10.4103/0973-1482.82924


Related references

Radiation-induced sarcoma after high-dose thoracic radiation therapy in non-small-cell lung cancer. Journal of Clinical Oncology 25(12): 1621-1623, 2007

External beam radiation therapy for bronchial stump recurrence of non-small-cell lung cancer after complete resection. Radiotherapy & Oncology 64(3): 251-257, September, 2002

Effect of duration of thoracic radiation therapy on the outcome of patients with limited small cell lung cancer treated with chemotherapy and radiation therapy. Radiotherapy & Oncology 56(Supplement 1): S57-S58, September, 2000

Prediction of radiation pneumonitis following high-dose thoracic radiation therapy by 3 Gy/fraction for non-small cell lung cancer: analysis of clinical and dosimetric factors. Japanese Journal of Clinical Oncology 39(3): 151-157, 2009

Prediction of radiation-induced changes in the lung after stereotactic body radiation therapy of non-small-cell lung cancer. International Journal of Radiation Oncology, Biology, Physics 67(3): 768-774, 2006

Risk factors for radiation-induced lung toxicity in patients with non-small cell lung cancer who received postoperative radiation therapy. Lung Cancer 77(2): 326-330, 2012

No thoracic radiation myelitis after spinal cord dose > or = 50.4 Gy using 1.2. Gy b.i.d. fractionation in patients with Stage III non-small cell lung cancer treated with hyperfractionated radiation therapy with and without concurrent chemotherapy. Lung Cancer 35(3): 287-292, 2002

The predictive role of plasma TGF-beta1 during radiation therapy for radiation-induced lung toxicity deserves further study in patients with non-small cell lung cancer. Lung Cancer 59(2): 232-239, 2007

Combining physical and biologic parameters to predict radiation-induced lung toxicity in patients with non-small-cell lung cancer treated with definitive radiation therapy. International Journal of Radiation Oncology, Biology, Physics 84(2): E217-E222, 2012

Phase I study of thoracic radiation dose escalation with concurrent chemotherapy for patients with limited small-cell lung cancer: Report of Radiation Therapy Oncology Group (RTOG) protocol 97-12. International Journal of Radiation Oncology, Biology, Physics 62(2): 342-350, 2005

Elevation of plasma TGF-beta1 during radiation therapy predicts radiation-induced lung toxicity in patients with non-small-cell lung cancer: a combined analysis from Beijing and Michigan. International Journal of Radiation Oncology, Biology, Physics 74(5): 1385-1390, 2009

Radiation-induced rib fractures after hypofractionated stereotactic body radiation therapy of non-small cell lung cancer: a dose- and volume-response analysis. RadioTherapy and Oncology 91(3): 360-368, 2009

Thoracic Radiation Therapy in Extensive Disease Small Cell Lung Cancer. International Journal of Radiation Oncology, Biology, Physics 93(1): 7-9, 2015

Analysis of clinical and dosimetric predictors of radiation-induced esophageal toxicity in patients with non-small cell lung cancer treated with three dimensional conformal radiation therapy. International Journal of Radiation Oncology Biology Physics 51(3 Supplement 1): 352, 2001