+ Most Popular
Cunninghamia lanceolata plantations in China
Mammalian lairs in paleo ecological studies and palynology
Studies on technological possibilities in utilization of anhydrous milk fat for production of recombined butter-like products
Should right-sided fibroelastomas be operated upon?
Large esophageal lipoma
Apoptosis in the mammalian thymus during normal histogenesis and under various in vitro and in vivo experimental conditions
Poissons characoides nouveaux ou non signales de l'Ilha do Bananal, Bresil
Desensitizing efficacy of Colgate Sensitive Maximum Strength and Fresh Mint Sensodyne dentifrices
Administration of fluid by subcutaneous infusion: revival of a forgotten method
Tundra mosquito control - an impossible dream?
Schizophrenia for primary care providers: how to contribute to the care of a vulnerable patient population
Geochemical pattern analysis; method of describing the Southeastern limestone regional aquifer system
Incidence of low birth weights in a hospital of Mexico City
Graded management intensity of grassland systems for enhancing floristic diversity
Microbiology and biochemistry of cheese and fermented milk
The ember tetra: a new pygmy characid tetra from the Rio das Mortes, Brazil, Hyphessobrycon amandae sp. n. (Pisces, Characoidei)
Risk factors of contrast-induced nephropathy in patients after coronary artery intervention
Renovation of onsite domestic wastewater in a poorly drained soil
Observations of the propagation velocity and formation mechanism of burst fractures caused by gunshot
Systolic blood pressure in a population of infants in the first year of life: the Brompton study
Haematological studies in rats fed with metanil yellow
Studies on pasteurellosis. I. A new species of Pasteurella encountered in chronic fowl cholera
Dormancy breaking and germination of Acacia salicina Lindl. seeds
therapy of lupus nephritis. a two-year prospective study

Radical-scavenging activity of dietary phytophenols in combination with co-antioxidants using the induction period method

Radical-scavenging activity of dietary phytophenols in combination with co-antioxidants using the induction period method

Molecules 16(12): 10457-10470

ISSN/ISBN: 1420-3049

PMID: 22173338

DOI: 10.3390/molecules161210457

The radical-scavenging activity of dietary phytophenols has been investigated by many researches due to their antioxidant, anti-inflammatory and anticancer property but the radical-scavenging effect of 2-phytophenol and the phytophenol:co-antioxidants, vitamin C and thiol combination under nearly anaerobic conditions still remains unknown. The radical-scavenging activity for seventeen phytophenols and for six synthetic phenols (positive controls) was investigated using the induction period method in the polymerization of methyl methacrylates (MMA) initiated by thermal decomposition of benzoyl peroxide (BPO) by monitoring differential scanning calorimetery (DSC). The k(inh) for the phytophenols was likely with the range 0.5 × 10³ M⁻¹s⁻¹-2.2 × 10³ M⁻¹s⁻¹, whereas that for synthetic phenols, hydroquinone and galvinoxyl, was with the range 7 × 10³ M⁻¹s⁻¹-8 × 10³ M⁻¹s⁻¹. Also, the additive scavenging effect of the (-)-epigallocatechin (EGC):(-)-epicatechin (EC) and the (+)-catechin:epicatechin (EC) combination was observed at 1:1 molar ratio, whereas that of the EC:quercetin combination showed the cancel (prooxidative) effect. Furthermore, the EGC:ASDB (L-ascorbyl 2,6-dibutylate) or 2-ME (2-mercaptoethanol) combination showed the prooxidative effect. Such enhancement of prooxidation in the combination may increase their toxic effects due to their cooxidation. Also, the synergic, additive or cancel effects of the flavonoid:vitamins E combination on the induction period in the BPO (a PhCOO* radical) and 2,2'-azobisisobutyronitrile (AIBN, an R* radical) systems are discussed.

Please choose payment method:

(PDF emailed within 0-6 h: $19.90)

Accession: 055346381

Download citation: RISBibTeXText

Related references

Radical-scavenging activity of melatonin, either alone or in combination with vitamin E, ascorbate or 2-mercaptoethanol as co-antioxidants, using the induction period method. In Vivo 25(1): 49-53, 2011

Radical-scavenging activity of natural methoxyphenols vs. synthetic ones using the induction period method. Molecules 12(2): 130-138, 2007

Comparative radical-scavenging activity of curcumin and tetrahydrocurcumin with thiols as measured by the induction period method. In Vivo 21(6): 979-982, 2007

Simple method for determining human serum 2,2-diphenyl-1-picryl-hydrazyl (DPPH) radical scavenging activity - possible application in clinical studies on dietary antioxidants. Clinical Chemistry and Laboratory Medicine 46(3): 342-349, 2008

Radical-scavenging activity of the reaction products of isoeugenol with thiol, thiophenol, mercaptothiazoline or mercaptomethylimidazole using the induction period method. Molecules 12(8): 1836-1844, 2007

Radical-scavenging Activity of Estrogen and Estrogen-like Compounds Using the Induction Period Method. International Journal of Molecular Sciences 8(4): 295-303, 2007

A novel method for evaluating free radical scavenging abilities of antioxidants using ultraviolet induction of bacteriophage lambda. Journal of Biochemical and Biophysical Methods 67(2-3): 163-171, 2006

A novel method of measuring hydroxyl radical-scavenging activity of antioxidants using gamma-irradiation. Free Radical Research 35(3): 265-271, 2001

A fluorometric method for measurement of oxygen radical-scavenging activity of water-soluble antioxidants. Analytical Biochemistry 284(1): 93-98, 2000

Novel hydroxyl radical scavenging antioxidant activity assay for water-soluble antioxidants using a modified CUPRAC method. Biochemical and Biophysical Research Communications 345(3): 1194-1200, 2006

A comparative study of the radical-scavenging activity of the phenolcarboxylic acids caffeic acid, p-coumaric acid, chlorogenic acid and ferulic acid, with or without 2-mercaptoethanol, a thiol, using the induction period method. Molecules 13(10): 2488-2499, 2008

2,2'-Azobis(isobutyronitrile)-derived alkylperoxyl radical scavenging activity assay of hydrophilic antioxidants by employing EPR spin trap method. Journal of Clinical Biochemistry and Nutrition 53(3): 134-138, 2013

Radical scavenging activity of antioxidants evaluated by means of electrogenerated HO radical. Talanta 129: 320-327, 2014

Solubilisation of a 2,2-diphenyl-1-picrylhydrazyl radical in water by β-cyclodextrin to evaluate the radical-scavenging activity of antioxidants in aqueous media. Chemical Communications 51(39): 8311-8314, 2015

Effects of noble metal nanoparticles on the hydroxyl radical scavenging ability of dietary antioxidants. Journal of Environmental Science and Health Part C 36(2): 84-97, 2018