+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Rare earths exposure and male infertility: the injury mechanism study of rare earths on male mice and human sperm

Rare earths exposure and male infertility: the injury mechanism study of rare earths on male mice and human sperm

Environmental Science and Pollution Research International 22(3): 2076-2086

The weight; testis/body coefficient; levels of LDH, SDH, SODH, G-6PD, and testosterone; cell cycle; and cell apoptosis of the male mice were influenced after being treated with 200 mg/[kg/day] of rare earths suspension for 3 weeks. The "Raman fingerprints" of the human sperm DNA exposed to 0.040 mg/ml CeCl3 were very different from those of the untreated; the Raman bands at 789 cm(-1) (backbone phosphodiester), PO4 backbone at 1,094 cm(-1), methylene deformation mode at 1,221 cm(-1), methylene deformation mode at 1,485 cm(-1), and amide II at 1,612 cm(-1), of which intensities and shifts were changed, might be the diagnostic biomarkers or potential therapeutic targets. The injury mechanism might be that the rare earths influence the oxidative stress and blood testosterone barrier, tangle the big biomolecule concurrently, which might cause the testicular cells and vascular system disorder and/or dysfunction, and at the same time change the physical and chemical properties of the sperm directly.

Please choose payment method:

(PDF emailed within 0-6 h: $19.90)

Accession: 055369960

Download citation: RISBibTeXText

PMID: 25167826

DOI: 10.1007/s11356-014-3499-y

Related references

Phase diagrams in rare earths-selenium and rare earths-tellur systems (ceric group rare earths). Colloques Internationaux du Centre National de la Recherche Scientifique 180(1): 471-481, 1970

Studies on rare earths in Mexico; Part 2, Petrology and mineralization of rare earths in the El Picacho igneous complex, Sierra de Tamaulipas. Boletin - Universidad Nacional Autonoma de Mexico, Instituto de Geologia 108: 24-97, 1990

Proposed rare earths production from the Mount Weld, WA, deposit of Ashton Rare Earths Limited. Monograph Series - Australasian Institute of Mining and Metallurgy 19: 1402-1405, 1993

Determination of total quantity of rare earths, Ca, Mg, Mn and Fe in rare-earths-magnesium by ICP-AES with offset profile add lines. Guang Pu Xue Yu Guang Pu Fen Xi 22(5): 838-839, 2002

Rare earths in lithogeochemistry; 1, Distribution scheme for rare earths in granites in the pegmatite area of Coronel Murta, Virgem da Lapa, Minas Gerais. Simposio Brasileiro de Geoquimica 3: 29-31, 1985

Rare earths and yeast fermentation. Part 3. On the physiological effects of rare earths. Archiv der Pharmazie und Berichte der Deutschen Pharmazeutischen Gesellschaft 293/65: 370-375, 1960

Separation of the rare earths by liquid ion exchange. V. Thin layer chromatographic separation of multiple component-mixtures of the rare earths. Journal of Chromatography 24(1): 153-160, 1966

The biological hormesis-effects of rare earths and potential effects of application of rare earths on agricultural eco-environment. Rural Eco Environment 20(4): 1-5, 2004

Separation of rare earths by liquid ion exchange. 3. Thin-layer chromatographic separation of rare earths. Journal of Chromatography 20(3): 580-584, 1965

Separation scheme for the determination of alkali metals (K, Rb, Cs), alkaline earths (Sr, Ba) and rare earths (Ce, Nd, Sm, Eu) in silicate materials by isotopic dilution analysis. Talanta 15(11): 1119-1124, 1968

Exposure, metabolism, and toxicity of rare earths and related compounds. Environmental Health Perspectives 104(Suppl. 1): 85-95, 1996

Prevention of vascular injury by dicoumarin, coumarin and the rare earths. Therapie der Gegenwart 93(3): 105-107, 1954

Research on the pharmacokinetics and distribution of the rare earths in mice. Southwest China Journal of Agricultural Sciences 19(6): 1166-1168, 2006

Supplement 1 || Exposure, Metabolism, and Toxicity of Rare Earths and Related Compounds. Environmental Health Perspectives 104: 85-95, 1996

Fluorocarbonates of rare earths; the principal industrial minerals of the rare earth elements. Izvestiya Vysshikh Uchebnykh Zavedeniy Geologiya i Razvedka, 1977