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Real time three-dimensional echocardiographic assessment of left ventricular regional systolic function and dyssynchrony in patients with dilated cardiomyopathy



Real time three-dimensional echocardiographic assessment of left ventricular regional systolic function and dyssynchrony in patients with dilated cardiomyopathy



Echocardiography 27(4): 415-420



To evaluate left ventricular (LV) regional systolic function and dyssynchrony in patients with dilated cardiomyopathy (DCM) by real time three-dimensional echocardiography (RT-3DE). The study population comprised 30 normal controls (NOR) and 44 patients with DCM. We divided the left ventricle into apical, middle, and basal regions. We calculated the LV regional end-diastolic volume ((R)EDV), regional end-systolic volume ((R)ESV), regional ejection fraction ((R)EF), and standard deviation in the time to minimal systolic volume in each level segment (Tmsv-SD) of the three regions by RT-3DE. Compared with NOR, the (R)EDV, (R)ESV, and Tmsv-SD of DCM were significantly higher, whereas the (R)EF was lower (P < 0.01). In DCM, the Tmsv-SD increased smoothly from base to apex, and the (R)EF gradually decreased from base to apex (P < 0. 05). Linear correlation was observed between the Tmsv-SD of the middle region and 3D-EF in DCM (r =-0. 6829, P < 0.01). RT-3DE provides a simple and feasible approach to quantify LV regional systolic function and dyssynchrony.

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Accession: 055389890

Download citation: RISBibTeXText

PMID: 20070354

DOI: 10.1111/j.1540-8175.2009.01028.x


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