+ Site Statistics
References:
54,258,434
Abstracts:
29,560,870
PMIDs:
28,072,757
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

Recent advances in microarray technologies for proteomics



Recent advances in microarray technologies for proteomics



Chemistry and Biology 20(5): 685-699



Proteins are fundamental components of all living systems and critical drivers of biological functions. The large-scale study of proteins, their structures and functions, is defined as proteomics. This systems-wide analysis leads to a more comprehensive view of the intricate signaling transduction pathways that proteins engage in and improves the overall understanding of the complex processes supporting the living systems. Over the last two decades, the development of high-throughput analytical tools, such as microarray technologies, capable of rapidly analyzing thousands of protein-functioning and protein-interacting events, has fueled the growth of this important field. Herein, we review the most recent advancements in microarray technologies, with a special focus on peptide microarray, small molecule microarray, and protein microarray. These technologies have become prominent players in proteomics and have made significant changes to the landscape of life science and biomedical research. We will elaborate on their performance, advantages, challenges, and future directions.

(PDF emailed within 0-6 h: $19.90)

Accession: 055398132

Download citation: RISBibTeXText

PMID: 23706635

DOI: 10.1016/j.chembiol.2013.04.009


Related references

Recent advances in peptide-based microarray technologies. Combinatorial Chemistry & High Throughput Screening 7(6): 547-556, 2004

Interactive proteomics research technologies: recent applications and advances. Current Opinion in Biotechnology 22(1): 50-58, 2011

Histochemical Technologies for Genomics and Proteomics: Laser Capture Microdissection (LCM) and Tissue Microarray (TMA). Acta Histochemica et Cytochemica 38(3): 185-188, 2005

Avian proteomics: advances, challenges and new technologies. Cytogenetic and Genome Research 117(1-4): 358-369, 2007

Proteomics: recent applications and new technologies. Basic and Clinical Pharmacology and Toxicology 98(5): 432-441, 2006

Current advances in peptide and small molecule microarray technologies. Current Opinion in Chemical Biology 16(1-2): 234-242, 2012

Recent Patents and Challenges on DNA Microarray Probe Design Technologies. Recent Patents on Dna & Gene Sequences 4(3): 210-217, 2010

Recent patents and challenges on DNA microarray probe design technologies. Recent Patents on Dna and Gene Sequences 4(3): 210-217, 2011

Recent advances in cardiovascular proteomics. Journal of Proteomics 81: 3-14, 2013

Recent advances in platelet proteomics. Expert Review of Proteomics 9(4): 451-466, 2013

Recent advances in proteomics of cereals. Biotechnology and Genetic Engineering Reviews 32(1-2): 1-17, 2017

Recent advances in membrane proteomics. Proteomics 8(19): 3919, 2008

Recent technical advances in proteomics. F1000research 8, 2019

Recent advances in capillary separations for proteomics. Electrophoresis 25(23-24): 3913-3926, 2004

Recent advances in blood-related proteomics. Proteomics 5(12): 3019-3034, 2005