+ Site Statistics
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

Recent advances in optical tweezers

Recent advances in optical tweezers

Annual Review of Biochemistry 77: 205-228

It has been over 20 years since the pioneering work of Arthur Ashkin, and in the intervening years, the field of optical tweezers has grown tremendously. Optical tweezers are now being used in the investigation of an increasing number of biochemical and biophysical processes, from the basic mechanical properties of biological polymers to the multitude of molecular machines that drive the internal dynamics of the cell. Innovation, however, continues in all areas of instrumentation and technique, with much of this work focusing on the refinement of established methods and on the integration of this tool with other forms of single-molecule manipulation or detection. Although technical in nature, these developments have important implications for the expanded use of optical tweezers in biochemical research and thus should be of general interest. In this review, we address these recent advances and speculate on possible future developments.

(PDF emailed within 0-6 h: $19.90)

Accession: 055398291

Download citation: RISBibTeXText

PMID: 18307407

DOI: 10.1146/annurev.biochem.77.043007.090225

Related references

Recent advances in magnetic tweezers. Annual Review of Biophysics 41: 453-472, 2013

Recent advances in laser tweezers Raman spectroscopy (LTRS) for label-free analysis of single cells. Journal of Biophotonics 6(1): 36-48, 2013

Micromanipulation of chromosomes in PTK2 cells using laser microsurgery (optical scalpel) in combination with laser-induced optical force (optical tweezers). Experimental Cell Research 204(1): 110-120, 1993

Recent advances in structural-optical mineralogy. Dizhi Kexue = Scientia Geologica Sinica 1979(2): 177-186, 1979

Recent advances in diffuse optical imaging. Physics in Medicine and Biology 50(4): R1-43, 2005

Recent advances in Optical Coherence Tomography. Rinsho Ganka 57(3): 221-227, March, 2003

Optical alignment and confinement of an ellipsoidal nanorod in optical tweezers: a theoretical study. Journal of the Optical Society of America. A, Optics, Image Science, and Vision 29(7): 1224-1236, 2012

Axial optical trapping forces on two particles trapped simultaneously by optical tweezers. Applied Optics 44(13): 2667-2672, 2005

Surface plasmon optical tweezers: tunable optical manipulation in the femtonewton range. Physical Review Letters 100(18): 186804-186804, 2008

Multiple holographic optical tweezers parallel calibration with optical potential well characterization. Optics Express 16(12): 9011-9020, 2008

Rotation of single bacterial cells relative to the optical axis using optical tweezers. Optics Letters 36(1): 40-42, 2011

Hands-on with optical tweezers: a multitouch interface for holographic optical trapping. Optics Express 17(5): 3595-3602, 2009

Optical levitation and manipulation of stuck particles with pulsed optical tweezers. Optics Letters 30(14): 1797-1799, 2005

Design of a high-quality optical conjugate structure in optical tweezers. Applied Optics 54(6): 1410-1413, 2015

Optical shield: measuring viscosity of turbid fluids using optical tweezers. Optics Express 20(11): 12127-12132, 2012