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Recent advances in stem and germ cell research: implications for the derivation of pig pluripotent cells



Recent advances in stem and germ cell research: implications for the derivation of pig pluripotent cells



Reproduction in Domestic Animals 47 Suppl 4: 98-106



Pluripotent stem cells have the unique capacity to contribute to all the tissues of an adult animal after transfer into a host embryo. How pluripotency is acquired during early development and how it is maintained in stem cells have attracted the interest of many scientists for over three decades. Much progress in our understanding of how stem cells arise in culture and the signals required for homoeostasis has enabled the derivation of pluripotent cells in multiple species. Here, we discuss recent developments in stem cell biology that will impact the generation of pluripotent cells from different embryonic origins and will contribute to increase our capacity for generating transgenic animals.

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Accession: 055398648

Download citation: RISBibTeXText

PMID: 22827357

DOI: 10.1111/j.1439-0531.2012.02062.x


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