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Regional white matter volumes correlate with delay discounting



Regional white matter volumes correlate with delay discounting



Plos One 7(2): E32595-E32595



A preference for immediate gratification is a central feature in addictive processes. However, the neural structures underlying reward delay tolerance are still unclear. Healthy participants (nā€Š=ā€Š121) completed a delay discounting questionnaire assessing the extent to which they prefer smaller immediate rewards to larger delayed reward after undergoing magnetic resonance imaging (MRI) scanning. Whole brain voxel-based morphometric analysis shows that delay discounting severity was negatively correlated with right prefrontal subgyral white matter volume and positively correlated with white matter volume in parahippocampus/hippocampus, after whole brain correction. This study might better our understanding of the neural basis of impulsivity and addiction.

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Accession: 055445283

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PMID: 22393420

DOI: 10.1371/journal.pone.0032595



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