Regioselectivity among six secondary hydroxyl groups: selective acylation of the least reactive hydroxyl groups of inositol
Vibhute, A.M.; Vidyasagar, A.; Sarala, S.; Sureshan, K.M.
Chemical Communications 48(18): 2448-2450
2012
ISSN/ISBN: 1364-548X PMID: 22266806 DOI: 10.1039/c2cc17241k
Accession: 055445930
We report the first, general and selective acylation of the least reactive hydroxyl group among six secondary hydroxyl groups of inositol in high yield, using very cheap and easy-to-make H(2)SO(4)-silica as the catalyst, providing easy access to bioactive molecules.
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