+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Comparison of microparticles produced with combinations of gelatin, chitosan and gum Arabic

Comparison of microparticles produced with combinations of gelatin, chitosan and gum Arabic

Carbohydrate Polymers 196: 427-432

The complexation between proteins and/or polysaccharides has been studied during decades and despite the knowledge of how these interactions occur provides a basis for identifying the conditions of microparticle formation, the presence of the oil phase complicates the application of available theory to explain the complexation between polymers. In this work, we identified some parameters which can interfere with this interaction, highlighting the influence of molecular arrangements by modifying the combination of gelatin (GE) and gum Arabic (GA) including the chitosan (CHI), a comparatively stronger polycation, to form particles in the presence or not of an essential oil. The results indicated the influence of the polymeric system in the morphological structure of particles as well as in the capacity of oil retention. The encapsulation of oil was more efficient for systems containing GA, due to the ability of these systems to form complexes. However, GE-GA particles presented as multinucleous while CHI-GA as a mononucleous structure.

Please choose payment method:

(PDF emailed within 0-6 h: $19.90)

Accession: 055532151

Download citation: RISBibTeXText

PMID: 29891315

DOI: 10.1016/j.carbpol.2018.05.027

Related references

Comparison of chitosan and gelatin coated microparticles: Prepared by hot-melt method. Journal of Microencapsulation 20(2): 169-177, March-April, 2003

Construction on the chitosan microparticles of baicalin and comparison of transdermal diffusion in vitro of baicalin in chitosan microparticles and cream. Zhong Yao Cai 35(5): 800-803, 2012

Production of microparticles with gelatin and chitosan. Carbohydrate Polymers 116: 292-299, 2015

Ultralow interfacial tensions in an aqueous phase-separated gelatin/dextran and gelatin/gum Arabic system: a comparison. Langmuir 20(6): 2292-2297, 2004

Release properties of chemical and enzymatic crosslinked gelatin-gum Arabic microparticles containing a fluorescent probe plus vetiver essential oil. Colloids and Surfaces. B Biointerfaces 67(2): 171-178, 2008

Use of gum arabic to improve the fabrication of chitosan-gelatin-based nanofibers for tissue engineering. Carbohydrate Polymers 115: 525-532, 2015

Properties of gelatin-based films incorporated with chitosan-coated microparticles charged with rutin. International Journal of Biological Macromolecules 101: 643-652, 2017

Mucoadhesive Buccal Tablets Based on Chitosan/Gelatin Microparticles for Delivery of Propranolol Hydrochloride. Journal of Pharmaceutical Sciences 104(12): 4365-4372, 2015

Synthesis of silver nanoparticles in chitosan, gelatin and chitosan/gelatin bionanocomposites by a chemical reducing agent and their characterization. Molecules 16(9): 7237-7248, 2011

Effects of the controlled-released basic fibroblast growth factor from chitosan-gelatin microspheres on human fibroblasts cultured on a chitosan-gelatin scaffold. Biomacromolecules 8(5): 1446-1455, 2007

Formulation and comparative characterization of chitosan, gelatin, and chitosan-gelatin-coated liposomes of CPT-11-HCl. Drug Development and Industrial Pharmacy 35(5): 612-618, 2009

Surface characterisation of bioadhesive PLGA/chitosan microparticles produced by supercritical fluid technology. Pharmaceutical Research 28(7): 1668-1682, 2011

Localised controlled release of simvastatin from porous chitosan-gelatin scaffolds engrafted with simvastatin loaded PLGA-microparticles for bone tissue engineering application. Materials Science and Engineering. C Materials for Biological Applications 59: 249-257, 2016

Comparison of Simple Eudragit Microparticles Loaded with Prednisolone and Eudragit-Coated Chitosan-Succinyl-Prednisolone Conjugate Microparticles: Part II. In Vivo Evaluation of Efficacy, Toxicity, and Biodisposition Characteristics. International Journal of Molecular Sciences 16(11): 26125-26136, 2015

Microencapsulation of sulforaphane from broccoli seed extracts by gelatin/gum arabic and gelatin/pectin complexes. Food Chemistry 201: 94, 2016