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Reversible hypothalamic dysfunction in optic nerve germinoma

Reversible hypothalamic dysfunction in optic nerve germinoma

Journal of Craniofacial Surgery 24(2): 468-469

Primary optic apparatus germ cell tumors are rare. There have been only 6 cases reported in the literature. Although they often disturb the hypothalamus-pituitary-adrenal axis and cause progressive visual loss, the influence of treatment outcomes on hypothalamic autoregulation has never been mentioned. Here, we report a patient with an optic nerve germinoma who presented with reversible visual and hypothalamic dysfunction, and we discuss the possible mechanisms and pathogenesis.

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Accession: 055557864

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PMID: 23524717

DOI: 10.1097/scs.0b013e318275eb2b

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