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Rheumatoid nodule in the lower lip of a patient with rheumatoid arthritis: a novel case report and review of literature



Rheumatoid nodule in the lower lip of a patient with rheumatoid arthritis: a novel case report and review of literature



Journal of Oral and Maxillofacial Surgery 72(8): 1532.E1-5



Rheumatoid nodules are a well-characterized common extra-articular manifestation of rheumatoid arthritis. However, the occurrence of a rheumatoid nodule in the oral mucosa is extremely rare. We present the case of a rheumatoid nodule in the lower lip, which rarely presents with variations in the clinical manifestation, that occurred in a 48-year-old female patient with rheumatoid arthritis. The nodule was totally excised under the clinical diagnosis of either a fibroma or salivary gland lesion. On histopathologic examination, within the deep mucosa, a necrobiotic nodule surrounded by elongated histiocytic cells with a focal palisaded arrangement. The lesion was diagnosed postoperatively as a rheumatoid nodule from the histopathologic and clinical findings. Few studies have been performed of oral rheumatoid lesions; however, a review of the published data showed that this is the first case of a rheumatoid nodule in the lower lip of a patient with rheumatoid arthritis.

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Accession: 055569390

Download citation: RISBibTeXText

PMID: 25037187

DOI: 10.1016/j.joms.2014.03.034


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