+ Site Statistics
References:
54,258,434
Abstracts:
29,560,870
PMIDs:
28,072,757
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

Risk factors associated with hospital admission among healthy children with adenovirus infection



Risk factors associated with hospital admission among healthy children with adenovirus infection



Turkish Journal of Pediatrics 53(6): 597-603



Adenovirus infections mimic bacterial infections on initial presentation in healthy children, leading to higher likelihood of hospital admission. The objective of this study was to identify risk factors associated with hospital admission in previously healthy children with adenovirus infection. This is a retrospective study of 125 previously healthy children, who tested positive with direct immunofluorescence assay (DFA) for adenoviral infection at our center between January 2001 and October 2007. The primary outcome of the study was the need for hospital admission. The relationship between clinical variables at initial emergency room (ER) presentation and need for hospital admission were explored using univariate and multivariate logistic regression models. The model's predictive value was investigated by calculating the area under the receiver operating characteristic (ROC) curve and Hosmer-Lemeshow test. On stepwise multivariate logistic regression analysis, the presence of respiratory distress (odds ratio [OR]: 5.6; p = 0.014), acute gastroenteritis (OR: 3.8; p = 0.019) and wheezes at initial presentation (OR: 6.5; p = 0.003) at the time of initial presentation in the ER were associated with need for hospital admission. For this model, the area under the ROC curve was 0.79, and there was no evidence of lack of fit on Hosmer-Lemeshow goodness-of-fit test (p = 0.56). Our study identifies three risk factors, namely, respiratory distress, wheezing and acute gastroenteritis, associated with hospital admission for healthy children with adenoviral infections.

(PDF emailed within 1 workday: $29.90)

Accession: 055579683

Download citation: RISBibTeXText

PMID: 22389981


Related references

Risk factors for severe respiratory syncytial virus infection leading to hospital admission in children in the Western Region of The Gambia. International Journal of Epidemiology 28(1): 157-162, 1999

Risk factors for hospital admission due to acute lower respiratory tract infection in Guarani indigenous children in southern Brazil: a population-based case-control study. Tropical Medicine & International Health 18(5): 596-607, 2013

Prevalence and risk factors for bloodstream infection present on hospital admission. Journal of Infection Prevention 19(1): 37-42, 2018

Is extended-spectrum beta-lactamase-producing Escherichia coli rectal carriage at hospital admission predictable? Risk factors at hospital admission. Journal of Hospital Infection 76(2): 178-180, 2010

Risk factors leading to hospital admission in Iranian asthmatic children. International Archives of Allergy and Immunology 145(3): 244-248, 2008

Respiratory syncytial virus infection--risk factors for hospital admission: a case-control study. Acta Paediatrica 92(11): 1314-1321, 2003

Preparation of healthy children for a hospital environment. A suggested method for preventing negative reactions by children on admission to hospital. Child Abuse & Neglect 6(4): 485-486, 1982

Risk factors for hospital admission of Brazilian children with non-rotavirus diarrhoea: a case control-study. Transactions of the Royal Society of Tropical Medicine and Hygiene 109(7): 454-461, 2016

Risk factors for admission to hospital with laboratory-confirmed influenza in young children: birth cohort study. European Respiratory Journal 50(3), 2017

Mixed infection and risk factors in children with severe adenovirus pneumonia. Zhongguo Dang Dai Er Ke Za Zhi 15(5): 375-378, 2013

Risk Factors for Severe Adenovirus Infection in Children during an Outbreak in Singapore. Annals of the Academy of Medicine, Singapore 44(2): 50-59, 2016

Risk factors for admission in children with Acute Gastroenteritis and dehydration presenting to a Pediatric Emergency Department at an Inner City Hospital. Pediatric Research 51(4 Part 2): 94A, April, 2002

African children with malaria in an area of intense Plasmodium falciparum transmission: features on admission to the hospital and risk factors for death. American Journal of Tropical Medicine and Hygiene 61(3): 431-438, 1999

Adenovirus respiratory infection in hospitalized children in Hong Kong: serotype-clinical syndrome association and risk factors for lower respiratory tract infection. European Journal of Pediatrics 173(3): 291-301, 2015

Identifying the risk factors for hospital-acquired methicillin-resistant Staphylococcus aureus (MRSA) infection among patients colonized with MRSA on admission. Infection Control and Hospital Epidemiology 33(12): 1219-1225, 2013