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Risk factors of contrast-induced nephropathy in patients after coronary artery intervention

Zhao, Y.-y.; Liu, D.-w.; Wang, J.-s.; Ouyang, J.; Zhang, W.-z.; Zhang, W.-j.; Meng, J.-q.; Tang, J.-m.

Zhonghua Yi Xue Za Zhi 92(22): 1547-1549

2012


ISSN/ISBN: 0376-2491
PMID: 22944059
Accession: 055583938

To explore the risk factors of contrast-induced nephropathy (CIN) in patients after coronary artery intervention. A total of 637 patients undergoing diagnostic coronary angiography or percutaneous coronary intervention were enrolled. They were divided into the CIN and non-CIN groups according to the changes in serum creatinine levels within 48 hours after coronary artery intervention. Then the relevant risk factors of CIN were analyzed. Among them, CIN occurred in 49 patients with an incidence of 7.7%. The patients with diabetes and renal insufficiency had higher incidence of CIN at 15.5% and 22.5% respectively. Logistic regression analysis showed that the risk factors of CIN included advanced age, smoking, diabetes, renal insufficiency, hypercholesterolemia and hyperuricemia. For the patients of coronary artery intervention, the major risk factors of CIN are advanced age, diabetes and renal insufficiency.

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