+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Safety and efficacy of sonographic-guided random real-time core needle biopsy of the liver

Safety and efficacy of sonographic-guided random real-time core needle biopsy of the liver

Journal of Clinical Ultrasound 37(3): 138-143

To determine the safety and efficacy of real-time, sonographic-guided, random percutaneous needle biopsy of the liver in a tertiary medical center. From an IRB-approved biopsy database, all patients who had random liver biopsy performed over a 24-month period were selected. In 350 patients, 539 random percutaneous needle biopsies of the liver were performed under real-time sonographic visualization. The following were recorded from the electronic medical record: patient demographics, indication for biopsy procedure; radiologist's name; needle type and gauge and number of passes; use and amount of i.v. sedation or anesthesia; adequacy of the specimen; and complications following the procedure. Of 539 biopsies, 378 (70%) biopsy procedures were performed on liver transplant recipients. Of the biopsy procedures in nontransplant patients, 81/161 (50%) concurrently underwent biopsy of a focal liver mass. An 18-gauge automated core biopsy needle was used in 536/539 (99%). Median number of passes per biopsy procedure was 1 (mean, 1.7; range, 1-6). Sedation using midazolam and fentanyl was used in 483/539 (90%). There were only 8 inadequate specimens (1.5%, [2.3, upper 95% confidence limit, fully described in Statistical Analysis]). Complications were identified in 11/539 biopsy procedures (2.0%, [2.6, upper 95% confidence limit]): 5 with severe postprocedural pain, 3 with symptomatic hemorrhage, 2 with infection, and 1 with a rash. There were no sedation-related complications and no deaths related to the procedure. Real-time, sonographic-guided, random core-needle liver biopsy is a safe and highly effective procedure.

Please choose payment method:

(PDF emailed within 0-6 h: $19.90)

Accession: 055642473

Download citation: RISBibTeXText

PMID: 19184991

DOI: 10.1002/jcu.20553

Related references

Safety and efficacy of sonographically guided random core biopsy for diffuse liver disease. Journal of Ultrasound in Medicine 19(8): 537-541, 2000

Comparison of the efficacy and safety of ultrasound-guided core needle biopsy versus fine-needle aspiration for evaluating thyroid nodules. Endocrine Practice 21(2): 128-135, 2016

Efficacy and safety of ultrasound (US) guided percutaneous needle biopsy for peripheral lung or pleural lesion: comparison with computed tomography (CT) guided needle biopsy. Journal of Thoracic Disease 11(3): 936-943, 2019

Transjugular liver biopsy: assessment of safety and efficacy of the Quick-Core biopsy needle. Abdominal Imaging 27(6): 711-715, 2002

Real-time ultrasound-guided renal biopsy with a biopsy gun in children: Safety and efficacy. Acta Paediatrica 90(12): 1394-1397, 2001

A stratified randomised study comparing the efficacy and safety of a standard tru-cut needle versus the automated tru-cut needle in percutaneous non-guided liver biopsy. Gastroenterology 112(4 SUPPL ): A11, 1997

Percutaneous real-time ultrasound-guided renal biopsy with automated biopsy gun in paediatrics Complications, safety and efficacy. Journal of the American Society of Nephrology 14(Abstracts Issue): 299A, 2003

Real-time three-dimensional optical coherence tomography image-guided core-needle biopsy system. Biomedical Optics Express 3(6): 1149-1161, 2012

Utility and Safety of Repeated Ultrasound-Guided Core Needle Biopsy of Focal Liver Masses. Journal of Ultrasound in Medicine 37(2): 447-452, 2017

Diagnostic accuracy and safety of US-guided core needle biopsy versus fine needle aspiration biopsy of thyroid nodules: a Meta analysis. Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 31(14): 1103-1107, 2018

Safety and efficacy of percutaneous CT-guided liver biopsy using an 18-gauge automated needle. European Journal of Internal Medicine 16(8): 571-574, 2005

Safety and efficacy of a spring-propelled 18-gauge needle for US-guided liver biopsy. Journal of Vascular and Interventional Radiology 2(1): 147-149, 1991

Real-time 3D fluoroscopy-guided large core needle biopsy of renal masses: a critical early evaluation according to the IDEAL recommendations. Cardiovascular and Interventional Radiology 35(3): 680-685, 2012

Evaluation of the efficacy and the limitation of ultrasound-guided core-needle biopsy, core-needle aspiration and fine-needle aspiration in micro-nodules of thyroid. Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 49(11): 893-896, 2015

Fine needle aspiration biopsy vs. ultrasound-guided transrectal random core biopsy of the prostate. Comparative investigations in 246 cases. Acta Cytologica 41(4): 981-986, 1997