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Scalable graphene field-effect sensors for specific protein detection

Scalable graphene field-effect sensors for specific protein detection

Nanotechnology 24(35): 355502

We demonstrate that micron-scale graphene field-effect transistor biosensors can be fabricated in a scalable fashion from large-area chemical vapor deposition derived graphene. We electrically detect the real-time binding and unbinding of a protein biomarker, thrombin, to and from aptamer-coated graphene surfaces. Our sensors have low background noise and high transconductance, comparable to exfoliated graphene devices. The devices are reusable and have a shelf-life greater than one week.

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Accession: 055656416

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PMID: 23917462

DOI: 10.1088/0957-4484/24/35/355502

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