+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Scleroderma renal crisis-like acute renal failure associated with mucopolysaccharide accumulation in renal vessels in a patient with scleromyxedema

Scleroderma renal crisis-like acute renal failure associated with mucopolysaccharide accumulation in renal vessels in a patient with scleromyxedema

Journal of Clinical Rheumatology 17(6): 318-322

Scleromyxedema is a systemic disease characterized by lichenoid papules, nodules, and plaques on the skin and often diffuse skin induration resembling the cutaneous involvement of systemic sclerosis. The systemic involvement affects the musculoskeletal, pulmonary, cardiovascular, gastrointestinal, and central nervous systems, and the disorder is commonly associated with a paraproteinemia. Involvement of the kidney is rare and not considered a feature of the disease. Here, we describe an unusual case of scleromyxedema complicated by the development of scleroderma renal crisis-like acute renal failure with a marked intimal deposition of mucin, mucopolysaccharides, and hyaluronic acid in the intrarenal vessels.

Please choose payment method:

(PDF emailed within 0-6 h: $19.90)

Accession: 055667978

Download citation: RISBibTeXText

PMID: 21869708

DOI: 10.1097/rhu.0b013e31822be61e

Related references

Scleroderma-like acute renal crisis in a patient with scleromyxedema. Nephrology Dialysis Transplantation 22(7): 2063-2067, 2007

A patient with acute renal failure. Scleroderma crisis (SRC). Netherlands Journal of Medicine 65(9): 360 361, 2007

Malignant hypertension and renal failure: scleroderma renal crisis or renal artery stenosis?. Nephrology Dialysis Transplantation 9(10): 1489-1491, 1994

Scleroderma renal crisis with severe renal failure A retrospective series of 18 patients. Journal of the American Society of Nephrology 11(Program and Abstract Issue): 161A, 2000

Hypertension and Renal Failure (Scleroderma Renal Crisis) in Progressive Systemic Sclerosis. Medicine 62(6): 335-352, 1983

ACE inhibitor-induced acute renal failure in a patient with progressive systemic sclerosis: ischemic nephropathy mimicking PSS renal crisis. Internal Medicine 46(18): 1605-1607, 2007

Exposure to ACE inhibitors prior to the onset of scleroderma renal crisis-results from the International Scleroderma Renal Crisis Survey. Seminars in Arthritis and Rheumatism 43(5): 666-672, 2014

Hypertension and renal failure (scleroderma renal crisis) in progressive systemic sclerosis. Review of a 25-year experience with 68 cases. Medicine 62(6): 335-352, 1983

Hemodynamics in acute renal failure. The effect of hypotension induced by dihydralazine on renal blood flow, mean circulation time for plasma, and renal vascular volume in patients with acute oliguric renal failure. Scandinavian Journal of Clinical and Laboratory Investigation 26(1): 83-87, 1970

Scleromyxedema associated with scleroderma renal disease and acute psychosis. Journal of the American Academy of Dermatology 14(5 Pt 2): 879-888, 1986

Renal handling of drugs in renal failure. I: Differential effects of uranyl nitrate- and glycerol-induced acute renal failure on renal excretion of TEAB and PAH in rats. Journal of Pharmacology and Experimental Therapeutics 246(3): 896-901, 1988

Enalapril induced reversible acute renal failure detected by (99m)Tc-DMSA renal scan in a patient with bilateral renal artery stenosis: a case report. Cases Journal 2: 7509, 2009

Acute kidney injury in a patient with systemic sclerosis: Looking beyond scleroderma renal crisis. Indian Journal of Nephrology 25(6): 387-388, 2015

Intriguing presentation of scleroderma renal crisis (scleroderma renal crisis sine scleroderma sine hypertension). Nephrology Dialysis Transplantation 13(11): 2953-2956, 1998

64-year-old patient with dyspnea at rest and rapidly progressing renal failure. Systemic sclerosis with interstitial lung disease and renal crisis. Der Internist 39(10): 1062-1068, 1998