+ Site Statistics
References:
54,258,434
Abstracts:
29,560,870
PMIDs:
28,072,757
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

Screening for and surveillance of gastric cancer



Screening for and surveillance of gastric cancer



World Journal of Gastroenterology 20(38): 13681-13691



Although the prevalence of gastric cancer (GC) progressively decreased during the last decades, due to improved dietary habit, introduction of food refrigeration and recovered socio-economic level, it still accounts for 10% of the total cancer-related deaths. The best strategy to reduce the mortality for GC is to schedule appropriate screening and surveillance programs, that rises many relevant concerns taking into account its worldwide variability, natural history, diagnostic tools, therapeutic strategies, and cost-effectiveness. Intestinal-type, the most frequent GC histotype, develops through a multistep process triggered by Helicobacter pylori (H. pylori) and progressing from gastritis to atrophy, intestinal metaplasia (IM), and dysplasia. However, the majority of patients infected with H. pylori and carrying premalignant lesions do not develop GC. Therefore, it remains unclear who should be screened, when the screening should be started and how the screening should be performed. It seems reasonable that screening programs should target the general population in eastern countries, at high prevalence of GC and the high-risk subjects in western countries, at low prevalence of GC. As far as concern surveillance, currently, we are lacking of standardized international recommendations and many features have to be defined regarding the optimal diagnostic approach, the patients at higher risk, the best timing and the cost-effectiveness. Anyway, patients with corpus atrophic gastritis, extensive incomplete IM and dysplasia should enter a surveillance program. At present, screening and surveillance programs need further studies to draw worldwide reliable recommendations and evaluate the impact on mortality for GC.

(PDF emailed within 1 workday: $29.90)

Accession: 055670980

Download citation: RISBibTeXText

PMID: 25320506


Related references

Screening and surveillance for gastric cancer in the United States: Is it needed?. Gastrointestinal Endoscopy 84(1): 18-28, 2017

Endoscopic gastric cancer screening and surveillance in high-risk groups. Clinical Endoscopy 47(6): 497-503, 2014

Is screening and surveillance for early detection of gastric cancer needed in Korean Americans?. Korean Journal of Internal Medicine 30(6): 747-758, 2016

Screening for gastric cancer and surveillance of premalignant lesions: a systematic review of cost-effectiveness studies. Helicobacter 18(5): 325-337, 2013

Is gastric cancer a new indication for surveillance colonoscopy? Colon cancer is increased in gastric cancer patients. Korean Journal of Gastroenterology 47(3): 191-197, 2006

Adherence to physician recommendations for surveillance in opportunistic colorectal cancer screening: the necessity of organized surveillance. Plos One 8(12): E82676, 2014

Current situation and future of gastric cancer screening examinations: from the viewpoint of gastric X-ray screening. Nihon Hoshasen Gijutsu Gakkai Zasshi 61(6): 881-886, 2005

Eradication of gastric cancer and more efficient gastric cancer surveillance in Japan: two peas in a pod. Journal of Gastroenterology 45(1): 1-8, 2010

PSA doubling time predicts the outcome after active surveillance in screening-detected prostate cancer: results from the European randomized study of screening for prostate cancer, Sweden section. International Journal of Cancer 120(1): 170-174, 2006

Characteristics of colon cancer detected by mass screening: A study of effective surveillance in mass screening for colorectal cancer. Journal of the Japan Society of Coloproctology 50(3): 149-154, 1997

Relative value of repeat gastric ulcer surveillance gastroscopy in diagnosing gastric cancer. Gastric Cancer 9(3): 217-222, 2006

Potential Biases Introduced by Conflating Screening and Diagnostic Testing in Colorectal Cancer Screening Surveillance. Cancer Epidemiology, Biomarkers and Prevention 24(12): 1850-1854, 2016

Who participates in the gastric cancer screening and on-time rescreening in the National Cancer Screening Program? A population-based study in Korea. Cancer Science 102(12): 2241-2247, 2012

Evaluation and revision of checklists for screening facilities and municipal governmental programs for gastric cancer and colorectal cancer screening in Japan. Japanese Journal of Clinical Oncology 40(11): 1021-1030, 2010

The current status of gastric cancer screening in Korea: report on the National Cancer Screening Programme, 2009. Asian Pacific Journal of Cancer Prevention 12(12): 3495-3500, 2012