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Seizure outcome following transcortical selective amygdalohippocampectomy in mesial temporal lobe epilepsy

Seizure outcome following transcortical selective amygdalohippocampectomy in mesial temporal lobe epilepsy

Stereotactic and Functional Neurosurgery 86(5): 314-319

The aim of this study was to retrospectively determine if patients with medically refractory epilepsy, due to hippocampal sclerosis, who underwent selective amygdalohippocampectomy (SAH) with a transcortical approach experienced improved seizure outcome. Thirty-nine patients with mesial temporal lobe epilepsy and hippocampal sclerosis were included in the study. The mean follow-up was 25.88 +/- 17.69 months. Antiepileptic medication use and seizure frequency were significantly reduced after SAH. After surgery, 32 patients (82.05%) were completely seizure free (Engel class IA), and 2 patients experienced transient memory difficulty. In conclusion, SAH with a transcortical approach can lead to favorable seizure control with a low irreversible complication risk.

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Accession: 055689279

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PMID: 18841036

DOI: 10.1159/000160154

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