+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Sentinel lymph node biopsy or nodal observation in melanoma: a prospective study of patient choices



Sentinel lymph node biopsy or nodal observation in melanoma: a prospective study of patient choices



Dermatologic Surgery 37(2): 199-206



There is no consensus regarding the therapeutic utility of sentinel lymph node biopsy (SLNB) versus that of nodal observation (NO) in melanoma. To prospectively evaluate a standardized counseling procedure and its effect on patient choices to undergo SLNB or NO. In four centers, patients with melanoma eligible for SLNB or NO received a complete counseling procedure that included verbal information from dermatologists and surgeons, a detailed information sheet, and a written consent form. Data collected included patient and tumor characteristics, counseling conditions, and specialties of informing doctors. Factors influencing patients' choices were studied using multivariate analysis. Of 343 consecutive patients, 309 were offered SLNB and NO and received complete verbal and written information from a dermatologist alone (62%) or in association with a surgeon (38%). Approximately half took advice from trusted persons, and half asked for additional time before making a decision; 268 (86.7%) ultimately decided to undergo SLNB. Multivariate analysis showed that older patients, those with a head and neck melanoma, and those informed without a surgeon present were more likely to prefer NO. This counseling procedure was easily implemented in clinical practice. Patients favored SLNB but were able to understand uncertainties and express preferences.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 055715337

Download citation: RISBibTeXText

PMID: 21269352

DOI: 10.1111/j.1524-4725.2010.01855.x


Related references

Sentinel lymph node biopsy or nodal observation in melanoma: study of an Italian series. Giornale Italiano di Dermatologia e Venereologia 148(3): 299-305, 2013

Compound Synthesis or Growth and Development of Roots/Stomata Regulate Plant Drought Tolerance or Water Use Efficiency/Water Uptake Efficiency. Journal of Agricultural and Food Chemistry 66(14): 3595-3604, 2018

Sentinel-node biopsy or nodal observation in melanoma. Current Oncology Reports 9(5): 401, 2007

Nodal Basin Recurrence After Sentinel Lymph Node Biopsy for Melanoma: A Retrospective Multicenter Study in 2653 Patients. Medicine 94(36): E1433, 2015

Prospective study of sentinel lymph node biopsy for conjunctival melanoma. British Journal of Ophthalmology 97(12): 1525-1529, 2013

Prospective study of fluorodeoxyglucose-positron emission tomography imaging of lymph node basins in melanoma patients undergoing sentinel node biopsy. Journal of Clinical Oncology 17(5): 1508-1515, 1999

Repeat sentinel lymph node biopsy in patients with ipsilateral recurrent breast cancer after breast-conserving therapy and negative sentinel lymph node biopsy: a prospective study. Minerva Chirurgica 71(2): 73-79, 2016

Prospective study of sentinel lymph node biopsy without further pelvic lymphadenectomy in patients with sentinel lymph node-negative cervical cancer. International Journal of Gynecological Cancer 22(7): 1244-1250, 2012

Final Results of the Sunbelt Melanoma Trial: A Multi-Institutional Prospective Randomized Phase III Study Evaluating the Role of Adjuvant High-Dose Interferon Alfa-2b and Completion Lymph Node Dissection for Patients Staged by Sentinel Lymph Node Biopsy. Journal of Clinical Oncology 34(10): 1079-1086, 2016

Final trial report of sentinel-node biopsy versus nodal observation in melanoma. New England Journal of Medicine 370(7): 599-609, 2014

Comparison between F-Fluorodeoxyglucose Positron Emission Tomography and Sentinel Lymph Node Biopsy for Regional Lymph Nodal Staging in Patients with Melanoma: A Review of the Literature. Radiology Research and Practice 2011: 912504, 2011

Identification of the lymph node drainage and selective sentinel lymph node biopsy in a patient with amelanotic melanoma of the uvula. Revista Espanola de Medicina Nuclear 30(5): 325-326, 2012

Sentinel lymph node biopsy in patients with thin melanoma: occurrence of nodal metastases and its prognostic value. European Journal of Dermatology 20(1): 30-34, 2010

Surgical management of sentinel lymph node biopsy outside major nodal basin in patients with cutaneous melanoma. Annals of Surgical Oncology 21(1): 300-305, 2014

Regional nodal basin control is not compromised by previous sentinel lymph node biopsy in patients with melanoma. Annals of Surgical Oncology 7(3): 226-231, 2000