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Serum carcinoembryonic antigen level in non-small-cell lung cancer patients with preoperative normal serum level



Serum carcinoembryonic antigen level in non-small-cell lung cancer patients with preoperative normal serum level



General Thoracic and Cardiovascular Surgery 57(6): 303-306



The prognostic significance of serum carcinoembryonic antigen (CEA) levels in non-small-cell lung cancer (NSCLC) patients with a normal serum CEA level (<5.0 ng/ml) was examined. A total of 220 consecutive NSCLC patients with preoperative normal serum CEA levels were included. Patients were subdivided into two groups: preoperative serum CEA level >/=2.5 and <2.5 ng/ml. The 5-year survival of patients with preoperative serum CEA level less and more than 2.5 ng/ml were 79.62% and 62.0%, respectively (P = 0.0036). Multivariate analysis indicated that a preoperative serum CEA level of >/=2.5 ng/ml was an independent prognostic factor. Similar results were found in patients with adenocarcinoma but not found in others. NSCLC patients with a high serum CEA level, especially adenocarcinoma patients, had poorer prognosis even if their serum CEA levels were within the normal upper limit.

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Accession: 055730003

Download citation: RISBibTeXText

PMID: 19533276

DOI: 10.1007/s11748-008-0397-6



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