+ Site Statistics
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

Severe imported Plasmodium falciparum malaria, France, 1996-2003

Severe imported Plasmodium falciparum malaria, France, 1996-2003

Emerging Infectious Diseases 17(5): 807-813

Little is known about severe imported Plasmodium falciparum malaria in industrialized countries where the disease is not endemic because most studies have been case reports or have included <200 patients. To identify factors independently associated with the severity of P. falciparum, we conducted a retrospective study using surveillance data obtained from 21,888 P. falciparum patients in France during 1996-2003; 832 were classified as having severe malaria. The global case-fatality rate was 0.4% and the rate of severe malaria was ≈3.8%. Factors independently associated with severe imported P. falciparum malaria were older age, European origin, travel to eastern Africa, absence of chemoprophylaxis, initial visit to a general practitioner, time to diagnosis of 4 to 12 days, and diagnosis during the fall-winter season. Pretravel advice should take into account these factors and promote the use of antimalarial chemoprophylaxis for every traveler, with a particular focus on nonimmune travelers and elderly persons.

(PDF emailed within 0-6 h: $19.90)

Accession: 055739775

Download citation: RISBibTeXText

PMID: 21529388

DOI: 10.3201/eid1705.101527

Related references

Risk factors for imported fatal Plasmodium falciparum malaria, France, 1996-2003. Emerging Infectious Diseases 13(6): 883-888, 2007

Propensity score analysis of artesunate versus quinine for severe imported Plasmodium falciparum malaria in France. Clinical Infectious Diseases 2019, 2019

Preferential expression of domain cassettes 4, 8 and 13 of Plasmodium falciparum erythrocyte membrane protein 1 in severe malaria imported in France. Clinical Microbiology and Infection 23(3): 211.E1-211.E4, 2016

Treatment with halofantrine of Plasmodium falciparum malaria imported into France. Bulletin de la Societe de Pathologie Exotique et de Ses Filiales 78(5 Pt 2): 965-970, 1985

Chemosensitivity of imported Plasmodium falciparum malaria in France in 1993. Medecine et Maladies Infectieuses 24(11): 1195-1197, 1994

Chemosensivity of imported Plasmodium falciparum malaria in France in 1989. Bulletin Epidemiologique Hebdomadaire ( 25): 107-109, 1990

Chemosusceptibility analysis of Plasmodium falciparum imported from Comoros to Marseilles, France in 2001-2003. Medecine et Maladies Infectieuses 35(10): 489-491, 2005

Profile and chemosensitivity of imported malaria due to Plasmodium falciparum in France, 2000. Bulletin Epidemiologique Hebdomadaire (26): 127-129, 2002

Parenteral Artesunate for Severe Imported Plasmodium falciparum Malaria in Children. Pediatric Infectious Disease Journal 35(9): 1053-1054, 2018

Simultaneous diagnosis of severe imported Plasmodium falciparum malaria and HIV: report of three cases. Malaria Journal 14: 266, 2016

Post-artesunate delayed haemolysis in severe imported Plasmodium falciparum malaria. Medical Journal of Australia 203(9): 364, 2016

Drug resistance of imported Plasmodium falciparum malaria in France in 1995: position of chloroquine and proguanil. Medecine d' Afrique Noire 43(12): 627-628, 1996

Imported malaria notified in New South Wales and the Australian Capital Territory, including trends in notifications of Plasmodium falciparum, 1989 to 2003. New South Wales Public Health Bulletin 16(5-6): 88-91, 2005

Imported Plasmodium falciparum malaria in Istanbul, Turkey: risk factors for severe course and mortality. Tropical Doctor 43(4): 129-133, 2013

Severe imported Plasmodium falciparum malaria in French paediatric intensive care units. Archives of Disease in Childhood 101(11): 989-990, 2016