+ Site Statistics
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

Severe infections in a cohort of patients with systemic lupus erythematosus

Severe infections in a cohort of patients with systemic lupus erythematosus

Medicina Clinica 135(8): 365-367

To study severe infectious complications in a cohort of patients with systemic lupus erythematosus (SLE). Retrospective study of 705 patients followed from January 1980 to January 2008. Data are expressed in percentages. The frequency of severe infectious was 38.6%. The etiology was bacterial 54.4%, viric 30.4% and opportunist in 15.2% patients. Involved organs were: Lung 38.2%, kidney 48.9%, central nervous system 43%. 43.75% patients received pulsed ciclofosfamide therapy and 88.6% received glucocorticoids (39.7% pulsed). The mortality was 27.7%. At present, infection is an important cause of mortality in patients with SLE. Early diagnosis of infectious complications is very important in SLE.

(PDF emailed within 0-6 h: $19.90)

Accession: 055739807

Download citation: RISBibTeXText

PMID: 20541779

DOI: 10.1016/j.medcli.2010.03.026

Related references

Classification of Systemic Lupus Erythematosus: Systemic Lupus International Collaborating Clinics Versus American College of Rheumatology Criteria. A Comparative Study of 2,055 Patients From a Real-Life, International Systemic Lupus Erythematosus Cohort. Arthritis Care & Research 67(8): 1180-1185, 2015

Systemic lupus erythematosus: clinical and immunologic patterns of disease expression in a cohort of 1,000 patients. The European Working Party on Systemic Lupus Erythematosus. Medicine 72(2): 113-124, 1993

Major infections in a cohort of 120 patients with juvenile-onset systemic lupus erythematosus. Clinical Immunology 149(3): 442-449, 2014

The use of Systemic Lupus Erythematosus Disease Activity Index-2000 to define active disease and minimal clinically meaningful change based on data from a large cohort of systemic lupus erythematosus patients. Rheumatology 50(5): 982-988, 2011

Neutropenia and the risk of infections in ambulatory patients with systemic lupus erythematosus: a three-year prospective study cohort. Lupus 20(9): 998-1000, 2011

Cutaneous lupus erythematosus and the association with systemic lupus erythematosus: a population-based cohort of 1088 patients in Sweden. British Journal of Dermatology 164(6): 1335-1341, 2012

Early discoid lupus erythematosus protects against renal disease in patients with systemic lupus erythematosus: longitudinal data from a large Latin American cohort. Lupus 26(1): 73-83, 2016

Factors associated with damage accrual in patients with systemic lupus erythematosus: results from the Systemic Lupus International Collaborating Clinics (SLICC) Inception Cohort. Annals of the Rheumatic Diseases 74(9): 1706-1713, 2015

Lymphopenia as risk factor for development of severe infections in patients with systemic lupus erythematosus: a case-control study. Qjm 106(5): 451-457, 2013

Progressive systemic sclerosis and localized scleroderma morphea with positive lupus erythematosus cell test and unusual systemic manifestations compatible with systemic lupus erythematosus presentation of 14 cases including 1 set of identical twins 1 with scleroderma and the other with systemic lupus erythematosus review of the literature. Medicine (Baltimore) 50(3): 199-222, 1971

Severe infections in plasmapheresis-treated systemic lupus erythematosus. Arthritis and Rheumatism 41(3): 414-420, 1998

Dystrophin Exon 29 Nonsense Mutations Cause a Variably Mild Phenotype. Ulster Medical Journal 86(3): 185-188, 2018

Euro-Lupus project Predictive value of antiphospholipid antibodies in a cohort of 913 patients with systemic lupus erythematosus. Arthritis & Rheumatism 38(9 SUPPL ): S170, 1995

Systemic lupus erythematosus in a multiethnic US cohort (LUMINA). XXV. Smoking, older age, disease activity, lupus anticoagulant, and glucocorticoid dose as risk factors for the occurrence of venous thrombosis in lupus patients. Arthritis and Rheumatism 52(7): 2060-2068, 2005

Characterization of Patients With Lupus Nephritis Included in a Large Cohort From the Spanish Society of Rheumatology Registry of Patients With Systemic Lupus Erythematosus (RELESSER). Medicine 95(9): E2891-E2891, 2016