+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Silver nanoparticles -- allies or adversaries?



Silver nanoparticles -- allies or adversaries?



Annals of Agricultural and Environmental Medicine 20(1): 48-54



Nanoparticles (NP) are structures with at least one dimension of less than 100 nanometers (nm) and unique properties. Silver nanoparticles (AgNP), due to their bactericidal action, have found practical applications in medicine, cosmetics, textiles, electronics, and other fields. Nevertheless, their less advantageous properties which make AgNP potentially harmful to public health or the environment should also be taken into consideration. These nanoparticles are cyto- and genotoxic and accumulate in the environment, where their antibacterial properties may be disadvantageous for agriculture and waste management. The presented study reviews data concerning the biological effects of AgNP in mammalian cells in vitro: cellular uptake and excretion, localization in cellular compartments, cytotoxicity and genotoxicity. The mechanism of nanoparticle action consists on induction of the oxidative stress resulting in a further ROS generation, DNA damage and activation of signaling leading to various, cell type-specific pathways to inflammation, apoptotic or necrotic death. In order to assure a safe application of AgNP, further detailed studies are needed on the mechanisms of the action of AgNP on mammalian cells at the molecular level.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 055778202

Download citation: RISBibTeXText

PMID: 23540211


Related references

From allies to adversaries?. American Psychologist 55(9): 1061-1062, 2000

Vendors: adversaries or allies?. Hospital Materiel Management Quarterly 5(4): 65-67, 1984

Medicine and law can be allies and adversaries. Geriatrics 27(1): 23 Passim, 1972

Hospitals and agencies: allies or adversaries?. Nursing Economic$ 6(5): 234-240, 1988

Hospitals, physicians need to be allies, not adversaries. Modern Healthcare 20(42): 50, 1990

Autophagy and viruses: adversaries or allies?. Journal of Innate Immunity 5(5): 480-493, 2013

Religion and medicine; allies or adversaries?. Gp 14(3): 75-81, 1956

Analytics turn adversaries into allies. Ahip Coverage 47(5): 42 44 46 Passim, 2006

Quality and cost: allies or adversaries?. Hospital Physician 22(10): 11 15, 1983

Materiel management and nursing: adversaries or allies?. Hospital Materiel Management Quarterly 7(2): 59-65, 1985

Hospitals and medical staffs: allies or adversaries?. Healthmarketing 3(2): 2-4, 1984

Planning and the invisible hand Allies or adversaries?. Planning Theory 12(2): 199-210, 2013

Information conversion: between physician allies and business adversaries. Administrative Radiology Journal 16(1): 26-29, 1997

Resource managers and field researchers: Allies or adversaries?. Great Barrier Reef Marine Park Authority Workshop Series 20: 17-26, 1994

The development of human female competition: allies and adversaries. Philosophical Transactions of the Royal Society of London. Series B Biological Sciences 368(1631): 20130079, 2013