+ Site Statistics
References:
54,258,434
Abstracts:
29,560,870
PMIDs:
28,072,757
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

Social phenotypes of autism spectrum disorders and williams syndrome: similarities and differences



Social phenotypes of autism spectrum disorders and williams syndrome: similarities and differences



Frontiers in Psychology 3: 247



Autism spectrum disorders (ASD) and Williams syndrome (WS) both are neurodevelopmental disorders, each with a unique social phenotypic pattern. This review article aims to define the similarities and differences between the social phenotypes of ASD and WS. We review studies that have examined individuals with WS using diagnostic assessments such as the Autism Diagnostic Observation Schedule (ADOS), cross-syndrome direct comparison studies, and studies that have individually examined either disorder. We conclude that (1) individuals with these disorders show quite contrasting phenotypes for face processing (i.e., preference to faces and eyes) and sociability (i.e., interest in and motivation to interact with others), and (2) although the ADOS and a direct comparison study on pragmatic language ability suggest more deficits in ASD, individuals with WS are similarly impaired on social cognition and communicative skills. In light of these results, we discuss how cross-syndrome comparisons between ASD and WS can contribute to developmental theory, cognitive neuroscience, and the development and choice of clinical treatments.

(PDF emailed within 0-6 h: $19.90)

Accession: 055829018

Download citation: RISBibTeXText

PMID: 22866045

DOI: 10.3389/fpsyg.2012.00247


Related references

What and why understanding in autism spectrum disorders and williams syndrome: similarities and differences. Autism Research 7(4): 421-432, 2015

Differences in Social Vulnerability among Individuals with Autism Spectrum Disorder, Williams Syndrome, and Down Syndrome. Research in Autism Spectrum Disorders 7(8): 931-937, 2013

Language and emotional abilities in children with Williams syndrome and children with autism spectrum disorder: similarities and differences. Pediatric Health, Medicine and Therapeutics 7: 89-97, 2016

Violations of Personal Space in Young People with Autism Spectrum Disorders and Williams Syndrome: Insights from the Social Responsiveness Scale. Journal of Autism and Developmental Disorders 45(12): 4101-4108, 2016

Association of mouse Dlg4 (PSD-95) gene deletion and human DLG4 gene variation with phenotypes relevant to autism spectrum disorders and Williams' syndrome. American Journal of Psychiatry 167(12): 1508-1517, 2011

Comparing parental stress of children with neurodevelopmental disorders: The case of Williams syndrome, Down syndrome and autism spectrum disorders. Journal of Applied Research in Intellectual Disabilities 2019, 2019

Parental views on special educational needs provision: Cross-syndrome comparisons in Williams Syndrome, Down Syndrome, and Autism Spectrum Disorders. Research in Developmental Disabilities 80: 102-111, 2018

Scan path differences and similarities during emotion perception in those with and without autism spectrum disorders. Journal of Autism and Developmental Disorders 38(7): 1371-1381, 2008

Anxiety and repetitive behaviours in autism spectrum disorders and williams syndrome: a cross-syndrome comparison. Journal of Autism and Developmental Disorders 42(2): 175-180, 2012

Rethinking the concepts of 'local or global processors': evidence from Williams syndrome, Down syndrome, and Autism Spectrum Disorders. Developmental Science 19(3): 452-468, 2017

Gaze aversion during social style interactions in autism spectrum disorder and Williams syndrome. Research in Developmental Disabilities 34(1): 616-626, 2013

Pragmatic language profiles of school-age children with autism spectrum disorders and Williams syndrome. American Journal of Speech-Language Pathology 16(4): 368-380, 2007

Association of GTF2i in the Williams-Beuren syndrome critical region with autism spectrum disorders. Journal of Autism and Developmental Disorders 42(7): 1459-1469, 2012

Global Similarities and Multifaceted Differences in the Production of Partner-Specific Referential Pacts by Adults with Autism Spectrum Disorders. Frontiers in Psychology 6: 1888, 2016

Social Skills Differences Between the Autism Spectrum Disorders. Journal of Developmental and Physical Disabilities 24(2): 125-134, 2012