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Specific serology for emerging human coronaviruses by protein microarray

Specific serology for emerging human coronaviruses by protein microarray

Euro Surveillance 18(14): 20441

We present a serological assay for the specific detection of IgM and IgG antibodies against the emerging human coronavirus hCoV-EMC and the SARS-CoV based on protein microarray technology. The assay uses the S1 receptor-binding subunit of the spike protein of hCoV-EMC and SARS-CoV as antigens. The assay has been validated extensively using putative cross-reacting sera of patient cohorts exposed to the four common hCoVs and sera from convalescent patients infected with hCoV-EMC or SARS-CoV.

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Accession: 055870348

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PMID: 23594517

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