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Squamous dysplasia and other precursor lesions related to esophageal squamous cell carcinoma



Squamous dysplasia and other precursor lesions related to esophageal squamous cell carcinoma



Gastroenterology Clinics of North America 36(4): 797-811, V-Vi



Squamous cell carcinoma is the most common tumor of the esophagus worldwide, and it is believed to develop through a sequence of dysplastic precursor lesions, which can be detected both endoscopically and microscopically. There are no published guidelines regarding treatment for dysplasia; however, most authorities recommend increased endoscopic surveillance, with biopsies, for patients with flat low-grade dysplasia and endoscopic mucosal resection, endoscopic submucosal dissection, or esophagectomy for patients with high-grade dysplasia. Future studies are needed to define appropriate endoscopic surveillance frequencies for patients with premalignant lesions of the esophagus. This article discusses squamous dysplasia in detail, which is the most important and well-described risk factor for squamous cell carcinoma of the esophagus.

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Accession: 055895944

Download citation: RISBibTeXText

PMID: 17996791

DOI: 10.1016/j.gtc.2007.08.005


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