+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Substantial family history of prostate cancer in black men recruited for prostate cancer screening: results from the Prostate Cancer Risk Assessment Program

Substantial family history of prostate cancer in black men recruited for prostate cancer screening: results from the Prostate Cancer Risk Assessment Program

Cancer 113(9): 2559-2564

Black men are at increased risk for prostate cancer (PCA), particularly with a family history (FH) of the disease. Previous reports have raised concern for suboptimal screening of black men with an FH of PCA. The extent of FH of PCA are reported from a prospective, longitudinal PCA screening program for high-risk men. Black men ages 35 to 69 years are eligible for PCA screening through the Prostate Cancer Risk Assessment Program (PRAP) regardless of FH. Rates of self-reported FH of PCA, breast, and colon cancer at baseline were compared with an age-matched sample of black men from the 2005 National Health Interview Survey (NHIS) using standard statistical methods. As of January 2007, 332 black men with pedigree information were enrolled in PRAP and FH of PCA was compared with 838 black men from the 2005 NHIS. Black men in PRAP reported significantly more first-degree relatives with PCA compared with black men in the 2005 NHIS (34.3% [95% confidence interval (95% CI), 29.2-39.7] vs 5.7% [95% CI, 3.9-7.4]). Black men in PRAP also had more FH of breast cancer compared with those in the 2005 NHIS (11.5% [95% CI, 8.2-15.4] vs 6.3% [95% CI, 4.6-8.0]). FH of PCA appears to be a motivating factor for black men seeking PCA screening. Targeted recruitment and education among black families should improve PCA screening rates. Efforts to recruit black men without an FH of PCA are also needed.

Please choose payment method:

(PDF emailed within 0-6 h: $19.90)

Accession: 055991828

Download citation: RISBibTeXText

PMID: 18816608

DOI: 10.1002/cncr.23862

Related references

A positive family history as a risk factor for prostate cancer in a population-based study with organised prostate-specific antigen screening: results of the Swiss European Randomised Study of Screening for Prostate Cancer (ERSPC, Aarau). Bju International 117(4): 576-583, 2016

Prostate cancer risk after stop-age in men participating in a long-term screening program: Results from the Gothenburg randomized population-based prostate-cancer screening trial. European Urology Suppl.s 18(1): e1521-e1522, 2019

Prostate cancer risk in men with prostate and breast cancer family history: results from the REDUCE study (R1). Journal of Internal Medicine 272(1): 85-92, 2012

Adding genetic risk score to family history identifies twice as many high-risk men for prostate cancer: Results from the prostate cancer prevention trial. Prostate 76(12): 1120-1129, 2017

Does positive family history of prostate cancer increase the risk of prostate cancer on initial prostate biopsy?. Urology 81(4): 826-830, 2013

Prostate cancer risk assessment in men with an initial P.S.A. below 3 ng/mL: results from the Göteborg randomized population-based prostate cancer screening trial. Scandinavian Journal of Urology 2018: 1-7, 2018

Characteristics of Prostate Cancer Found at Fifth Screening in the European Randomized Study of Screening for Prostate Cancer Rotterdam: Can We Selectively Detect High-grade Prostate Cancer with Upfront Multivariable Risk Stratification and Magnetic Resonance Imaging?. European Urology 2017, 2017

Prostate-specific antigen-based prostate cancer screening: reduction of prostate cancer mortality after correction for nonattendance and contamination in the Rotterdam section of the European Randomized Study of Screening for Prostate Cancer. European Urology 65(2): 329-336, 2014

The association between metabolic syndrome and the risk of prostate cancer, high-grade prostate cancer, advanced prostate cancer, prostate cancer-specific mortality and biochemical recurrence. Journal of Experimental and Clinical Cancer Research 32: 9, 2013

Family history of prostate cancer and prostate cancer risk in the Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study. International Journal of Cancer 123(5): 1154-1159, 2008

Body Mass Index And Prostate Size Improve Performance Of A Prostate Cancer Risk Calculator At High Levels Of Sensitivity For Predicting Prostate Cancer At Initial Prostate Biopsy: Results From A Prospective, Multi-Center Cohort. The Journal of Urology 183(4): e818-e819, 2010

Prostate cancer risk prediction using the novel versions of the European Randomised Study for Screening of Prostate Cancer (ERSPC) and Prostate Cancer Prevention Trial (PCPT) risk calculators: independent validation and comparison in a contemporary European cohort. Bju International 117(3): 401-408, 2016

Do the risk factors of age, family history of prostate cancer or a higher prostate specific antigen level raise anxiety at prostate biopsy?. European Journal of Cancer 45(14): 2569-2573, 2009

Prostate cancer detection in Brazil Results of a prostate cancer screening program of 1464 patients. Journal of Urology 157(4 Suppl. ): 233, 1997

Prostate cancer screening in men with a family history of prostate cancer: the role of partners in influencing men's screening uptake. Urology 70(4): 738-742, 2007