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Synthesis of oxindoles by tandem Heck-reduction-cyclization (HRC) from a single bifunctional, in situ generated Pd/C catalyst

Synthesis of oxindoles by tandem Heck-reduction-cyclization (HRC) from a single bifunctional, in situ generated Pd/C catalyst

Journal of Organic Chemistry 74(3): 1349-1352

A tandem sequence involving palladium-catalyzed sequential Heck-reduction-cyclization transformations in mild conditions has been developed for the synthesis of oxindoles. The protocol involves inexpensive reagents and does not require any additives such as base or ligands.

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Accession: 056080846

Download citation: RISBibTeXText

PMID: 19113937

DOI: 10.1021/jo802467s

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