+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

The Cleveland Clinic PediPump: anatomic modeling and virtual fitting studies in a lamb model



The Cleveland Clinic PediPump: anatomic modeling and virtual fitting studies in a lamb model



Asaio Journal 53(6): 716-719



Implantation of ventricular assist devices (VADs) is challenging in small patients with limited space in the chest. We created three-dimensional models of lambs to facilitate fitting of the PediPump, a pediatric VAD currently under development. Serial computed tomography (CT) scans were acquired at multiple time points (n = 8) for three lambs. Digital models were created using these CT datasets and three-dimensional image processing software (Mimics, Materialise). Pixels representing the heart and chest wall were rendered as three-dimensional models. Using three-dimensional model manipulation software (Magics RP, Materialise), on-screen models of extravascular and intravascular VADs were placed in right, left and biventricular support configurations to determine optimal placement. A cannulation strategy was established and in some cases three-dimensional models of the inflow and outflow grafts were created. After the final CT study, an open-chest fitting study was performed using rapid prototype models of the pediatric VAD and cannulas. The pump location and orientation predictions from the virtual fitting studies matched those determined at the time of the open-chest fitting studies. Using three-dimensional modeling, we have established a fitting protocol that facilitates animal implantations; the same modeling techniques may be useful for device fitting in humans.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 056173696

Download citation: RISBibTeXText

PMID: 18043154

DOI: 10.1097/mat.0b013e31805fe98b


Related references

Cleveland Clinic PediPump lamb cadaver fitting studies. Artificial Organs 31(5): 405-408, 2007

The Cleveland Clinic PediPump: virtual fitting studies in children using three-dimensional reconstructions of cardiac computed tomography scans. Asaio Journal 54(1): 133-137, 2008

Initial acute in vivo performance of the Cleveland Clinic PediPump left ventricular assist device. Asaio Journal 53(6): 766-770, 2007

Short-term in vivo performance of the Cleveland clinic PediPump left ventricular assist device. Artificial Organs 38(5): 374-382, 2014

Human Fitting Studies of Cleveland Clinic Continuous-Flow Total Artificial Heart. Asaio Journal 61(4): 424-428, 2016

Establishing an Anatomic Pathology Laboratory at Cleveland Clinic Abu Dhabi. Archives of Pathology and Laboratory Medicine 142(9): 1036-1046, 2018

Setting Up an ePathology Service at Cleveland Clinic Abu Dhabi: Joint Collaboration With Cleveland Clinic, United States. Archives of Pathology and Laboratory Medicine 142(10): 1216-1222, 2018

Virtual Fitting, Selection, and Cutting of Preformed Anatomic Orbital Implants. Ophthalmic Plastic and Reconstructive Surgery 33(3): 196-201, 2016

Intra-operative fitting study of the PediPump ventricular assist device. Journal of Heart and Lung Transplantation 31(1): 109-110, 2012

Simulated Performance of the Cleveland Clinic Continuous-Flow Total Artificial Heart Using the Virtual Mock Loop. Asaio Journal 65(6): 565-572, 2019

External validation of Cleveland Clinic Foundation colorectal cancer model in a University Clinic in terms of predicting operative mortality. Techniques in Coloproctology 14(1): 9, 2010

Can Cleveland Clinic Health System be trusted: whether a proposed merger or acquisition by Cleveland Clinic Health System will substantially impair the competitive health care market in northeast Ohio resulting in a violation of federal antitrust statutes. Journal of Law and Health 17(1): 137-168, 2004

Clinical centers of excellence: Infertility. Cleveland Clinic, Cleveland, Ohio. Medical Economics 86(19): 49, 2009

Obstetric anesthesia training in the USA, experience of the Cleveland Clinic; Cleveland, Ohio. Masui. Japanese Journal of Anesthesiology 58(9): 1179-1186, 2009

A day in the busy obstetric unit from the anesthesiologist point of view, experience at the Cleveland clinic; Cleveland, Ohio. Masui. Japanese Journal of Anesthesiology 58(10): 1328-1335, 2009