EurekaMag
+ Translate
+ Most Popular
Gaucher's disease;thirty-two years experience at Siriraj Hospital
A study of Macrobathra Meyrick from China (Lepidoptera, Cosmopterigidae)
First occurrence in ores of tetragonal chalcocite
Effects of trace element nutrition on sleep patterns in adult women
N.Z. range management guidelines. 2. Design of grazing management systems for tussock country
A case of lipoma of the esophagus
A revision of world Acanthosomatidae (Heteroptera: Pentatomidae): keys to and descriptions of subfamilies, tribes and genera, with designation of types
Life history of the coronate scyphozoan Linuche unguiculata (Swartz, 1788)
Perceptual restoration of obliterated sounds
Mutagenicity studies on two chromium(III) coordination compounds
The formation of the skeleton. I. Growth of a long bone. 1st appearance of a center of calcification
Leucopenia and abnormal liver function in travellers on malaria chemoprophylaxis
The joint commission: four key root causes loom large in sentinel event data
Treatment of vitiligo with topical 15% lactic acid solution in combination with ultra violet-A
Behaviour of dairy cows within three hours after feed supply: I. Influence of housing type and time elapsing after feed supply
Observations of the propagation velocity and formation mechanism of burst fractures caused by gunshot
Management and control of patients with type 2 diabetes mellitus in Lebanon: results from the International Diabetes Management Practices Study (IDMPS)
The diet composition and nutritional knowledge of patients with anorexia nervosa
Physoporella croatica Herak, 1958 of the Slovak karst Anisian (Slovakia, the West Carpathians Mts.)
Bright lights, big noise. How effective are vehicle warning systems?
Ein Plesiosaurier-Rest mit Magensteinen aus mittlerem Lias von Quedlinburg
Incidence of Chlamydia trachomatis in patients with sterility
Monster soup: the microscope and Victorian fantasy
Preliminary tests with residual sprays against poultry lice
Duration of the life of plants in phylogeny

The first case of bloodstream infection by Candida intermedia in Japan: the importance of molecular identification


The first case of bloodstream infection by Candida intermedia in Japan: the importance of molecular identification



Journal of infection and chemotherapy: official journal of the Japan Society of Chemotherapy 17(4): 555-558



ISSN/ISBN: 1341-321X

PMID: 21302127

DOI: 10.1007/s10156-011-0215-4

A 65-year-old Chinese man with diabetes mellitus was admitted to our hospital complaining of bloody sputum, fever, and dyspnea. Despite antibiotic treatment, his condition deteriorated, necessitating mechanical ventilation. Diffuse alveolar hemorrhage was suspected, and steroid therapy was initiated. Although his condition improved and he was extubated, the fever recurred twice, and on both occasions blood cultures yielded yeasts. The yeasts were misidentified as Cryptococcus humicola with a commercially available phenotype test (API ID32C), which did not match the clinical profile, and molecular identification was then performed. The isolates were identified as Candida intermedia by molecular phylogenetic analyses of the chromosomal regions coding for the D1/D2 domain of the large-subunit 26S rRNA gene. The patient responded well to several antifungal agents and was discharged on the 34th hospital day. To our knowledge, this is the first case of C. intermedia infection reported in Japan, and the tenth case reported in the international medical literature.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 056344149

Download citation: RISBibTeXText

Related references

Bilateral Candida endophthalmitis accompanying Candida lusitaniae bloodstream infection: A case report. Journal of Infection and Chemotherapy: Official Journal of the Japan Society of ChemoTherapy 24(2): 147-149, 2018

A case of breakthrough Candida parapsilosis fungemia during micafungin therapy for a Candida glabrata bloodstream infection. Medical Mycology Case Reports 16: 1-3, 2017

Comparison of API20C with molecular identification of Candida spp isolated from bloodstream infections. Journal of Clinical Pathology 55(10): 774-777, 2002

First case report of bloodstream infection due to a Candida species closely related to the novel species Candida pseudorugosa. Journal of Clinical Microbiology 50(6): 2165-2169, 2012

Three novel species of the anamorphic yeast genus Candida in the Candida intermedia clade found in Japan, Thailand and Taiwan. Journal of General and Applied Microbiology 57(2): 73-81, 2011

First case of bloodstream infection due to Candida magnoliae in a Chinese oncological patient. Journal of Clinical Microbiology 45(10): 3470-3473, 2007

Molecular Identification and Echinocandin Susceptibility of Candida parapsilosis Complex Bloodstream Isolates in Italy, 2007-2014. PloS one 11(2): e0150218, 2016

First case reports of bloodstream infection by Candida magnoliae in two neonates with low birth weight. International Journal of Pediatrics and Adolescent Medicine 5(4): 159-161, 2018

Candida dubliniensis bloodstream infection: a fatal case in a lung transplant recipient. Transplant Infectious Disease: An Official Journal of the Transplantation Society 7(3-4): 146-149, 2005

Enhanced Molecular Diagnosis of Bloodstream Candida Infection with Size-Based Inertial Sorting at Submicron Resolution. Analytical Chemistry 92(23): 15579-15586, 2020

Bloodstream infection with Candida kefyr/Kluyveromyces marxianus: case report and draft genome. Clinical Microbiology and Infection: the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases 2019, 2020

Risk factors and outcomes of Candida krusei bloodstream infection: a matched, case-control study. Journal of Infection 66(3): 278-284, 2013

Case-Case Comparison of Candida auris Versus Other Candida Species Bloodstream Infections: Results of an Outbreak Investigation in Colombia. Mycopathologia 185(5): 917-923, 2020

Pretreatment Conditions for Hydrolysates from Unbleached Pulp Waste for Ethanol Fermentation with Xylose-fermenting Yeast, Candida intermedia 4-6-4T2; Candida intermedia 4-6-4T2;. Journal of the Japan Petroleum Institute 61(3): 191-198, 2018

Rapid identification of Candida glabrata in Candida bloodstream infections. Journal of Medical Microbiology 56(Pt 12): 1639-1643, 2007