+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

The meiotic recombination hotspots of Schizosaccharomyces pombe



The meiotic recombination hotspots of Schizosaccharomyces pombe



Genome Dynamics 5: 1-13



Meiotic recombination predominantly occurs at genomic loci referred to as recombination hotspots. The fission yeast, Schizosaccharomyces pombe, has proved to be an excellent model organism in which to study details of the molecular basis of meiotic recombination hotspot activation. S. pombe has a number of different classes of meiotic hotspots, indicating that a single pathway does not confer hotspot activity throughout the genome. The M26-related hotspots are a particularly well characterised group of hotspots and details of the molecular activation of M26-related hotspots are now coming to light. Moreover, genome-wide DNA array analysis has been applied to the question of meiotic recombination in this organism and we are now starting to get a picture of recombination hotspot distribution on a genome-wide scale.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 056404852

Download citation: RISBibTeXText

PMID: 18948703

DOI: 10.1159/000166614


Related references

Novel nucleotide sequence motifs that produce hotspots of meiotic recombination in Schizosaccharomyces pombe. Genetics 182(2): 459-469, 2009

The Rad52 homologs Rad22 and Rti1 of Schizosaccharomyces pombe are not essential for meiotic interhomolog recombination, but are required for meiotic intrachromosomal recombination and mating-type-related DNA repair. Genetics 178(4): 2399-2412, 2008

Important characteristics of sequence-specific recombination hotspots in Schizosaccharomyces pombe. Genetics 187(2): 385-396, 2011

Control of meiotic recombination in Schizosaccharomyces pombe. Progress in Nucleic Acid Research and Molecular Biology 61: 345-378, 1998

The meiotic recombination hot spot ura4A in Schizosaccharomyces pombe. Genetics 169(2): 551-561, 2005

Meiotic recombination-deficient mutants of Schizosaccharomyces pombe. Genetics 123(1): 45-54, 1989

Genetic analysis of meiotic recombination in Schizosaccharomyces pombe. Methods in Molecular Biology 557: 65-76, 2009

Meiotic recombination and chromosome segregation in Schizosaccharomyces pombe. Proceedings of the National Academy of Sciences of the United States of America 98(15): 8395-8402, 2001

Five RecA-like proteins of Schizosaccharomyces pombe are involved in meiotic recombination. Genetics 165(3): 1031-1043, 2003

Linear element-independent meiotic recombination in Schizosaccharomyces pombe. Genetics 174(3): 1105-1114, 2006

Meiotic recombination in schizosaccharomyces pombe genes enzymes and sites. Gottesman, M E And H J Vogel (Ed ) Mechanisms Of Eukaryotic Dna Recombination Xi+215p Academic Press, Inc : San Diego, California, Usa; London, England, Uk Illus 155-166, 1992

Dmc1 of Schizosaccharomyces pombe plays a role in meiotic recombination. Nucleic Acids Research 28(14): 2709-2716, 2000

Suppression of Meiotic Recombination by CENP-B Homologs in Schizosaccharomyces pombe. Genetics 201(3): 897-904, 2015

Region-specific activators of meiotic recombination in Schizosaccharomyces pombe. Genes and Development 8(2): 203-210, 1994

Differential activation of M26-containing meiotic recombination hot spots in Schizosaccharomyces pombe. Genetics 170(1): 95, 2005