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The oncological emergency case: paraneoplastic hypoglycemia in metastatic breast cancer - case report and brief review of the literature



The oncological emergency case: paraneoplastic hypoglycemia in metastatic breast cancer - case report and brief review of the literature



Breast Care 8(5): 368-370



Paraneoplastic hypoglycemia is a rare syndrome amoung tumorous diseases. It is often associated with a paraneoplastic secretion of 'big' insulin-like growth factor-II. We describe this syndrome in a 60-year-old patient with advanced breast cancer 8 years after primary diagnosis. This non-islet cell tumor-induced hypoglycemia may be the only evidence for an otherwise clinically occult disease progression. Fast diagnosis and appropriate acute and causal treatment concepts should be part of oncological management. Die paraneoplastische Hypoglykämie ist ein seltenes Syndrom im Zusammenhang mit Tumorerkrankungen. Sie ist häufig mit einer paraneoplastischen Sekretion von «big»-Insulin-like Growth Factor-II (IGF-II) assoziiert. Der vorliegende Fallbericht beschreibt das Syndrom bei einer 60-jährigen Patientin mit fortgeschrittenem Mammakarzinom 8 Jahre nach Erstdiagnose. Die Nicht-Insellzelltumor-induzierte paraneoplastische Hypo-glykämie (NICTH) kann ein Hinweis auf einen bisher nicht diagnostizierten Tumorprogress sein. Die Diagnosestellung sowie die adäquate Akut- und Kausaltherapie gehören ins Repertoire des Onkologen.

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Accession: 056422571

Download citation: RISBibTeXText

PMID: 24415991

DOI: 10.1159/000355702


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