+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

The relationship of coffee and green tea consumption with high-sensitivity C-reactive protein in Japanese men and women



The relationship of coffee and green tea consumption with high-sensitivity C-reactive protein in Japanese men and women



Clinical Chemistry and Laboratory Medicine 48(6): 849-854



Circulating high-sensitivity C-reactive protein (CRP) is a good marker of chronic low-grade inflammation. The few studies that have addressed the relationship between coffee consumption and CRP concentrations report inconsistent findings. The authors of this study examined the relationship between coffee and green tea consumption and serum concentrations of CRP, and the interaction with alcohol consumption, smoking, and obesity in a large population of free-living Japanese men and women. Study subjects were 10,325 men and women, 49-76 years of age, living in Fukuoka City who participated in a baseline survey of a cohort study on lifestyle-related diseases. Coffee and green tea consumption and other lifestyle characteristics were assessed using a structured questionnaire. Anthropometric measurements and venous blood samples were also included. CRP concentrations were progressively lower with increasing levels of coffee consumption, after adjustment for smoking and other covariates (p for trend=0.03) in men, but not in women. Stratified analysis indicated that this inverse association was primarily limited to men with a high consumption of alcohol (> or =50 g/day). Green tea consumption showed no measurable relationship with CRP concentrations in either men or women. Coffee may be protective specifically against alcohol-induced hepatic inflammation. Further studies are warranted in different populations.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 056461904

Download citation: RISBibTeXText

PMID: 20441477

DOI: 10.1515/cclm.2010.161


Related references

The relationship between usual coffee consumption and serum C-reactive protein level in a Japanese female population. Clinical Chemistry and Laboratory Medicine 46(10): 1434-1437, 2008

Combined effects of coffee consumption and serum γ-glutamyltransferase on serum C-reactive protein in middle-aged and elderly Japanese men and women. Clinical Chemistry and Laboratory Medicine 49(10): 1661-1667, 2011

Behavioral and clinical correlates of high-sensitivity C-reactive protein in Japanese men and women. Clinical Chemistry and Laboratory Medicine 50(8): 1469-1476, 2012

The relationship between sleep-disordered breathing and high-sensitivity C-reactive protein in Japanese men. Sleep 29(5): 661-665, 2006

Relationship between coffee and green tea consumption and all-cause mortality in a cohort of a rural Japanese population. Journal of Epidemiology 12(3): 191-198, 2002

Relationship Between Serum High-Sensitivity C-Reactive Protein and Myocardial Infarction in a General Japanese Population. Journal of Clinical Laboratory Analysis 30(6): 999-1002, 2016

Coffee, green tea, black tea and oolong tea consumption and risk of mortality from cardiovascular disease in Japanese men and women. Journal of Epidemiology and Community Health 65(3): 230-240, 2011

Association between consumption of beer, wine, and liquor and plasma concentration of high-sensitivity C-reactive protein in women aged 39 to 89 years. American Journal of Cardiology 96(1): 83-88, 2005

Consumption of coffee, green tea, oolong tea, black tea, chocolate snacks and the caffeine content in relation to risk of diabetes in Japanese men and women. British Journal of Nutrition 103(3): 453-459, 2010

Inverse associations of serum bilirubin with high sensitivity C-reactive protein, glycated hemoglobin, and prevalence of type 2 diabetes in middle-aged and elderly Japanese men and women. Diabetes Research and Clinical Practice 88(1): 103-110, 2010

Association between coffee consumption and the estimated glomerular filtration rate in the general Japanese population: preliminary data regarding C-reactive protein concentrations. Clinical Chemistry and Laboratory Medicine 48(12): 1773-1776, 2010

Evaluation of high-sensitivity C-reactive protein in comparison with C-reactive protein as biochemical serum markers in women with endometriosis. Fertility and Sterility 93(7): 2125-2129, 2010

Coffee consumption but not green tea consumption is associated with adiponectin levels in Japanese males. European Journal of Nutrition 50(4): 279-284, 2011

Assessing self-reported green tea and coffee consumption by food frequency questionnaire and food record and their association with polyphenol biomarkers in Japanese women. Asia Pacific Journal of Clinical Nutrition 27(2): 460-465, 2018

The relationship between specific Fatty acids of serum lipids and serum high sensitivity C- reactive protein levels in morbidly obese women. Cellular Physiology and Biochemistry 34(4): 1101-1108, 2014