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The stochastic evolution of a protocell: the Gillespie algorithm in a dynamically varying volume



The stochastic evolution of a protocell: the Gillespie algorithm in a dynamically varying volume



Computational and Mathematical Methods in Medicine 2012: 423627



We propose an improvement of the Gillespie algorithm allowing us to study the time evolution of an ensemble of chemical reactions occurring in a varying volume, whose growth is directly related to the amount of some specific molecules, belonging to the reactions set. This allows us to study the stochastic evolution of a protocell, whose volume increases because of the production of container molecules. Several protocell models are considered and compared with the deterministic models.

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Accession: 056503563

Download citation: RISBibTeXText

PMID: 22536297

DOI: 10.1155/2012/423627


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