+ Site Statistics
References:
54,258,434
Abstracts:
29,560,870
PMIDs:
28,072,757
+ Search Articles
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ PDF Full Text
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Translate
+ Recently Requested

The use of stimulant medications for non-core aspects of ADHD and in other disorders



The use of stimulant medications for non-core aspects of ADHD and in other disorders



Neuropharmacology 87: 161-172



Psychostimulants play a central role in the management of ADHD. Here we review the evidence pertaining to the use of methylphenidate, dexamphetamine and related amphetamine salts, the prodrug lisdexamfetamine and modafinil for the management of comorbid ADHD and non-ADHD indications. There is a growing consensus that stimulant medications are helpful at improving the emotional dysregulation and lability, and oppositional and conduct symptoms that are often associated with ADHD. There is some evidence that psychostimulants may improve outcomes in those with treatment resistant depression, reduce negative symptoms and improve cognitive performance in schizophrenia, and that methylphenidate may reduce binge eating in those with bulimia nervosa. In general medicine, whilst the evidence is at times contradictory, psychostimulants have been shown in some studies to be effective treatments for chronic fatigue and narcolepsy, and to improve outcomes post stroke, post head injury, in dementia and various cancers. It seems likely that these effects often result from a combination of, reduction in fatigue, improvements in concentration and cognitive functioning and a lifting of mood which may be a direct or indirect consequence of the medication. Further studies seem warranted and these should focus on efficacy, effectiveness and long term safety. This article is part of the Special Issue entitled 'CNS Stimulants'.

(PDF emailed within 0-6 h: $19.90)

Accession: 056528605

Download citation: RISBibTeXText

PMID: 24951855

DOI: 10.1016/j.neuropharm.2014.06.014


Related references

A qualitative review of issues arising in the use of psycho-stimulant medications in patients with ADHD and co-morbid substance use disorders. Current Medical Research and Opinion 24(5): 1345-1357, 2008

ADHD and substance use disorders: developmental aspects and the impact of stimulant treatment. American Journal on Addictions 16 Suppl 1: 5-11; Quiz 12-3, 2007

Stimulant medications for attention-deficit/hyperactivity disorder (ADHD) improve memory of emotional stimuli in ADHD-diagnosed college students. Pharmacology, Biochemistry, and Behavior 105: 58-62, 2013

Non-stimulant medications in the treatment of ADHD. European Child and Adolescent Psychiatry 13 Suppl 1: I102-I116, 2004

The effects of stimulant medications for ADHD. National Bureau of Economic Research Bulletin on Aging and Health: 1-2, 2014

Cardiovascular Effects of Stimulant Medications Taken for ADHD. Aap Grand Rounds 15(1): 4-5, 2006

Cardiac reactivity and stimulant use in adolescents with autism spectrum disorders with comorbid ADHD versus ADHD. Journal of Autism and Developmental Disorders 45(2): 481-494, 2015

The Effects of Stimulant Medications on the Art Products of ADHD Children. Art Therapy 9(1): 36-41, 1992

Stimulant medications: a trade-off? The lived experience of adolescents with ADHD. Journal for Specialists in Pediatric Nursing 11(4): 214-226, 2006

Stimulant Medications and Sleep for Youth With ADHD: A Meta-analysis. Pediatrics 136(6): 1144-1153, 2016

Do stimulant medications improve educational and behavioral outcomes for children with ADHD?. Journal of Health Economics 37: 58-69, 2016

Methamphetamine psychosis: Lack of association with stimulant prescription ADHD medications. American Journal of Emergency Medicine 2019, 2019

Duration of effect of oral long-acting stimulant medications for ADHD throughout the day. Current Medical Research and Opinion 26(8): 1809-1825, 2010

Stimulant Medications Decrease Risk of Substance Abuse in Children with ADHD. Aap Grand Rounds 2(5): 51-51, 1999

Pharmacotherapy in ADHD. Guidelines for prescribing stimulant medications in young children. Minnesota Medicine 83(6): 45-46, 2000