Trends in the technology-driven development of new inhalation devices
Frijlink, H.W.; de Boer, A.H.
Drug Discovery Today. Technologies 2(1): 47-57
2005
ISSN/ISBN: 1740-6749 PMID: 24981755 DOI: 10.1016/j.ddtec.2005.05.020
Accession: 056688032
Inhalation technology diverges rapidly along various lines. A variety of technological solutions are currently under development to overcome the many problems related to adequate aerosol generation both for dry powder inhalation systems and for liquid inhalation systems. Many of the improvements are related to the fine particle fraction in the generated aerosol, particularly its dependency on the patients' inspiratory flow profile and the velocity of the aerosol.: