+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Virtual topological optimisation of scaffolds for rapid prototyping



Virtual topological optimisation of scaffolds for rapid prototyping



Medical Engineering and Physics 32(7): 775-782



Advanced additive techniques are now being developed to fabricate scaffolds with controlled architecture for tissue engineering. These techniques combine computer-aided design (CAD) with computer-aided manufacturing (CAM) tools to produce three-dimensional structures layer by layer in a multitude of materials. Actual prediction of the effective mechanical properties of scaffolds produced by additive technologies, is very important for tissue engineering applications. A novel computer based technique for scaffold design is topological optimisation. Topological optimisation is a form of "shape" optimisation, usually referred to as "layout" optimisation. The goal of topological optimisation is to find the best use of material for a body that is subjected to either a single load or a multiple load distribution. This paper proposes a topological optimisation scheme in order to obtain the ideal topological architectures of scaffolds, maximising its mechanical behaviour.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 056876301

Download citation: RISBibTeXText

PMID: 20620093

DOI: 10.1016/j.medengphy.2010.05.001


Related references

Rapid prototyping composite and complex scaffolds with PAM2. Methods in Molecular Biology 868: 57-69, 2012

Rapid prototyping of hydrogel structures-scaffolds for artificial organs. International Journal of Artificial Organs 25(7): 622-623, 2002

Production of new 3D scaffolds for bone tissue regeneration by rapid prototyping. Journal of Materials Science. Materials in Medicine 27(4): 69, 2016

Rapid prototyping--when virtual meets reality. International Journal of Computerized Dentistry 17(4): 297-306, 2014

The design of scaffolds for use in tissue engineering. Part II. Rapid prototyping techniques. Tissue Engineering 8(1): 1-11, 2002

3D polycaprolactone scaffolds with controlled pore structure using a rapid prototyping system. Journal of Materials Science. Materials in Medicine 20(1): 229-234, 2009

Weak two-photon absorption applied to the rapid prototyping of cell scaffolds. Applied Optics 55(2): 228-235, 2016

Fabrication using a rapid prototyping system and in vitro characterization of PEG-PCL-PLA scaffolds for tissue engineering. Journal of Biomaterials Science. Polymer Edition 16(12): 1595-1610, 2005

Reconstruction of comminuted long-bone fracture using CF/CPC scaffolds manufactured by rapid prototyping. Medical Science Monitor 18(11): Br435-Br440, 2012

Porous titanium scaffolds fabricated using a rapid prototyping and powder metallurgy technique. Biomaterials 29(27): 3625-3635, 2008

Rapid and low-cost prototyping of 3D nanostructures with multi-layer hydrogen silsesquioxane scaffolds. Small 9(24): 4237-4242, 2013

Fabrication and characterization of novel nano- and micro-HA/PCL composite scaffolds using a modified rapid prototyping process. Journal of Biomedical Materials Research. Part a 89(1): 108-116, 2009

Rapid prototyping of scaffolds derived from thermoreversible hydrogels and tailored for applications in tissue engineering. Biomaterials 23(23): 4437-4447, 2002

Development of novel hybrid poly(L-lactide)/chitosan scaffolds using the rapid freeze prototyping technique. Biofabrication 3(3): 034105, 2011

Rapid prototyping and 3D-virtual models for operative dentistry education in Brazil. Journal of Dental Education 77(3): 358-363, 2013