+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Virtual touch tissue quantification using acoustic radiation force impulse technology: initial clinical experience with solid breast masses



Virtual touch tissue quantification using acoustic radiation force impulse technology: initial clinical experience with solid breast masses



Journal of Ultrasound in Medicine 31(2): 289-294



The purpose of this study was to investigate the clinical usage of Virtual Touch tissue quantification (VTQ; Siemens Medical Solutions, Mountain View, CA) implementing sonographic acoustic radiation force impulse technology for differentiation between benign and malignant solid breast masses. A total of 143 solid breast masses were examined with VTQ, and their shear wave velocities (SWVs) were measured. From all of the masses, 30 were examined by two independent operators to evaluate the reproducibility of the results of VTQ measurement. All masses were later surgically resected, and the histologic results were correlated with the SWV results. A receiver operating characteristic curve was calculated to assess the diagnostic performance of VTQ. A total of 102 benign lesions and 41 carcinomas were diagnosed on the basis of histologic examination. The VTQ measurements performed by the two independent operators yielded a correlation coefficient of 0.885. Applying a cutoff point of 3.065 m/s, a significant difference (P < .001) was found between the SWVs of the benign (mean ± SD, 2.25 ± 0.59 m/s) and malignant (5.96 ± 2.96 m/s) masses. The sensitivity, specificity, and area under the receiver operating characteristic curve for the differentiation were 75.6%, 95.1%, and 85.6%, respectively. When the repeated non-numeric result X.XX of the SWV measurements was designated as an indicator of malignancy, the sensitivity, specificity, and accuracy were 63.4%, 100%, and 89.5%. Virtual Touch tissue quantification can yield reproducible and quantitative diagnostic information on solid breast masses and serve as an effective diagnostic tool for differentiation between benign and malignant solid masses.

Please choose payment method:






(PDF emailed within 1 workday: $29.90)

Accession: 056876304

Download citation: RISBibTeXText

PMID: 22298873


Related references

Acoustic radiation force impulse imaging with Virtual Touch™ tissue quantification: mean shear wave velocity of malignant and benign breast masses. International Journal of Women's Health 5: 619-627, 2013

Virtual Touch quantification using acoustic radiation force impulse (ARFI) technology for the evaluation of focal solid renal lesions: preliminary findings. Clinical Radiology 70(12): 1376-1381, 2015

Acoustic radiation force impulse imaging with virtual touch tissue quantification: measurements of normal breast tissue and dependence on the degree of pre-compression. Ultrasound in Medicine and Biology 39(12): 2226-2232, 2013

Combination of elastography and tissue quantification using the acoustic radiation force impulse (ARFI) technology for differential diagnosis of breast masses. Japanese Journal of Radiology 30(8): 659-670, 2012

Reliable measurement procedure of virtual touch tissue quantification with acoustic radiation force impulse imaging. Journal of Ultrasound in Medicine 30(6): 745-751, 2011

Acoustic Radiation Force Impulse (ARFI) technique in ultrasound with Virtual Touch tissue quantification of the upper abdomen. La Radiologia Medica 115(6): 889-897, 2010

Reliable measurement by virtual touch tissue quantification with acoustic radiation force impulse imaging: phantom study. Journal of Ultrasound in Medicine 31(8): 1239-1244, 2012

Reliability analysis of acoustic radiation force impulse ultrasound imaging with virtual touch tissue quantification: ex vivo ox liver. Ultrasound Quarterly 31(1): 59-62, 2015

Virtual touch tissue quantification of acoustic radiation force impulse: a new ultrasound elastic imaging in the diagnosis of thyroid nodules. Plos one 7(11): E49094, 2012

Differentiation of benign and malignant focal liver lesions: value of virtual touch tissue quantification of acoustic radiation force impulse elastography. Medical Oncology 32(3): 68, 2015

Acoustic radiation force impulse (ARFI) imaging with Virtual Touch Tissue Quantification in liver disease associated with cystic fibrosis in children. La Radiologia Medica 117(8): 1408-1418, 2012

Ultrasonographic tissue quantification of the breast using acoustic radiation force impulse technology: phantom study and clinical application. Japanese Journal of Radiology 29(8): 598-603, 2011

Acoustic Radiation Force Impulse Imaging With Virtual Touch Tissue Quantification Enables Characterization of Mild Hypoxic-Ischemic Brain Damage in Neonatal Rats. Journal of Ultrasound in Medicine 38(7): 1797-1805, 2019

Acoustic Radiation Force Impulse Technology in the Differential Diagnosis of Solid Breast Masses with Different Sizes: Which Features Are Most Efficient?. Biomed Research International 2015: 410560, 2015

Clinical application of Acoustic Radiation Force Impulse Imaging with Virtual Touch IQ in breast ultrasound: diagnostic performance and reproducibility of a new technique. Acta Radiologica 58(2): 140-147, 2017