EurekaMag.com logo
+ Site Statistics
References:
47,893,527
Abstracts:
28,296,643
+ Search Articles
+ Subscribe to Site Feeds
EurekaMag Most Shared ContentMost Shared
EurekaMag PDF Full Text ContentPDF Full Text
+ PDF Full Text
Request PDF Full TextRequest PDF Full Text
+ Follow Us
Follow on FacebookFollow on Facebook
Follow on TwitterFollow on Twitter
Follow on Google+Follow on Google+
Follow on LinkedInFollow on LinkedIn

+ Translate

What is the role of pleuropneumonectomy in malignant pleural mesothelioma?


, : What is the role of pleuropneumonectomy in malignant pleural mesothelioma?. Nihon Geka Gakkai Zasshi 110(6): 343-347

In this report, the results of conventional pleuropneumonectomy in malignant diffuse mesothelioma are reviewed, and the role of this aggressive surgery in multidisciplinary treatment is discussed. The surgical results may improve owing to recent advances in medical technology, although the postoperative survival time after pleuropneumonectomy has remained nearly the same for the past 40 years. The problems with pleuropneumonectomy are high mortality and morbidity rates, high local recurrence rates, and almost the same survival rates as seen after pleurectomy. The indications for this aggressive surgery are limited to stage I, II, and III disease based on an accurate staging system, with induction therapy for macroscopic radical resection and postoperative chemoradiation therapy. In addition, patients must be monitored for the development of major complications perioperatively. The natural history of this disease should be clarified to determine the effectiveness of various forms of therapy. Precise analysis of the accumulated data from many institutions will help to improve the results of pleuropneumonectomy.


Accession: 056922958

PMID: 19999569

Submit PDF Full Text: Here


Submit PDF Full Text

No spam - Every submission is manually reviewed

Due to poor quality, we do not accept files from Researchgate

Submitted PDF Full Texts will always be free for everyone
(We only charge for PDFs that we need to acquire)

Select a PDF file:
Close
Close

Related references

Grondin, S.C.; Sugarbaker, D.J., 2000: Pleuropneumonectomy in the treatment of malignant pleural mesothelioma. Malignant pleural mesothelioma (MPM) is predominantly a local/regional disease that results in a survival time that ranges from 4 to 12 months without treatment. Single-modality therapy using surgery, chemotherapy, or radiotherapy alone is largely...

Takagi, K., 2008: Pleuropneumonectomy: an effective treatment modality for malignant pleural mesothelioma?. Annals of Thoracic and Cardiovascular Surgery 14(3): 135-137

Sato K.; Maeno H.; Dambara T.; E.A., 1988: A case of diffuse pleural malignant mesothelioma treated with pleuropneumonectomy. The patient was a 67 year-old man suffering from left chest pain and left anterior chest swelling. Chest X-ray examination showed diffuse and irregular left pleural thickening. Needle and open biopsy from left anterior chest mass revealed diffuse...

Krayenbuehl, Jôme.; Hartmann, M.; Lomax, A.J.; Kloeck, S.; Hug, E.B.; Ciernik, I.Frank., 2010: Proton therapy for malignant pleural mesothelioma after extrapleural pleuropneumonectomy. To perform comparative planning for intensity-modulated radiotherapy (IMRT) and proton therapy (PT) for malignant pleural mesothelioma after radical surgery. Eight patients treated with IMRT after extrapleural pleuropneumonectomy (EPP) were replan...

Bonnette, P.; Heckly, G.Bourg.; Villette, S.; Fragola, A., 2002: Intraoperative photodynamic therapy after pleuropneumonectomy for malignant pleural mesothelioma. Chest 122(5): 1866-7; Author Reply 1867

Schouwink, J., H.; Bass, P., 2002: Intraoperative photodynamic therapy after pleuropneumonectomy for malignant pleural mesothelioma: Response. Chest 122(5): 1867

Milazzo, M.; Magrone, G.; Romanelli, A.; Ronconi, G.; Gallotta, E.; Sterzi, S., 2008: Evaluation of the rehabilitation program in a patient submitted to pleuropneumonectomy for malignant pleural mesothelioma. The purpose of this study is to test a rehabilitation program for the patients with malignant pleural mesothelioma (MPM) subordinates to pleuropneumonectomy. A single patient was evaluated at baseline (TI) and at the end of the pulmonary rehabilit...

Hahnloser, P.; Geroulanos, S., 1976: Reconstruction of the diaphragm with a pericardial flap after radical pleuropneumonectomy for malignant pleural mesothelioma. Pleuropneunomectomy with resection of the diaphragm only offers acceptable therapeutic results in patients with multifocal malignant mesothelioma of the pleura. Diaphragmatic replacement on the right side can be satisfactorily achieved by fixation...

Schouwink, H.; Rutgers, E.T.; Van Der Sijp, J.; Oppelaar, H.; Van Zandwijk, N.; Van Veen, R.; Burgers, S.; Stewart, F.A.; Zoetmulder, F.; Baas, P., 2001: Intraoperative photodynamic therapy after pleuropneumonectomy in patients with malignant pleural mesothelioma. Does finding and toxicity results. Objective: To determine the optimal administered dose of meta-tetrahydroxyphenylchlorin (mTHPC) for intraoperative photodynamic therapy (IPDT) in resected malignant pleural mesothelioma (MPM). The primary objective of this combination treatment wa...

Schouwink, H.; Rutgers, E.T.; van der Sijp, J.; Oppelaar, H.; van Zandwijk, N.; van Veen, R.; Burgers, S.; Stewart, F.A.; Zoetmulder, F.; Baas, P., 2001: Intraoperative photodynamic therapy after pleuropneumonectomy in patients with malignant pleural mesothelioma: dose finding and toxicity results. To determine the optimal administered dose of meta-tetrahydroxyphenylchlorin (mTHPC) for intraoperative photodynamic therapy (IPDT) in resected malignant pleural mesothelioma (MPM). The primary objective of this combination treatment was to improv...