Xenotropic murine leukemia virus-related virus prevalence in patients with chronic fatigue syndrome or chronic immunomodulatory conditions
Henrich, T.J.; Li, J.Z.; Felsenstein, D.; Kotton, C.N.; Plenge, R.M.; Pereyra, F.; Marty, F.M.; Lin, N.H.; Grazioso, P.; Crochiere, D.M.; Eggers, D.; Kuritzkes, D.R.; Tsibris, A.M.N.
Journal of Infectious Diseases 202(10): 1478-1481
ISSN/ISBN: 1537-6613 PMID: 20936980 DOI: 10.1086/657168
We investigated the prevalence of xenotropic murine leukemia virus-related virus (XMRV) among 293 participants seen at academic hospitals in Boston, Massachusetts. Participants were recruited from the following 5 groups of patients: chronic fatigue syndrome (n = 32), human immunodeficiency virus infection (n = 43), rheumatoid arthritis (n = 97), hematopoietic stem-cell or solid organ transplant (n = 26), or a general cohort of patients presenting for medical care (n = 95). XMRV DNA was not detected in any participant samples. We found no association between XMRV and patients with chronic fatigue syndrome or chronic immunomodulatory conditions.