Section 57
Chapter 56,970

Xenotropic murine leukemia virus-related virus proviral DNA not detected in blood samples donated in Japan

Matsumoto, C.; Igarashi, M.; Furuta, R.A.; Uchida, S.; Satake, M.; Tadokoro, K.

Japanese Journal of Infectious Diseases 65(4): 334-336


ISSN/ISBN: 1884-2836
PMID: 22814159
Accession: 056969524

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The xenotropic murine leukemia virus-related virus (XMRV) was first described as a novel human gammaretrovirus in prostate tumor tissues and was reported to be found in blood, suggesting the possibility of XMRV transmission via blood transfusion. The gag and env regions of the XMRV proviral DNA that were detected 1,030 blood samples collected from the greater Tokyo area were examined by real-time PCR analysis. However, XMRV infection was not found in the samples; this suggested that the risk of XMRV transmission via transfusion is very low in Japan.

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