+ Site Statistics
+ Search Articles
+ PDF Full Text Service
How our service works
Request PDF Full Text
+ Follow Us
Follow on Facebook
Follow on Twitter
Follow on LinkedIn
+ Subscribe to Site Feeds
Most Shared
PDF Full Text
+ Translate
+ Recently Requested

Acoustic radiation force impulse elastography for differentiation of benign and malignant thyroid nodules with concurrent Hashimoto's thyroiditis



Acoustic radiation force impulse elastography for differentiation of benign and malignant thyroid nodules with concurrent Hashimoto's thyroiditis



Medical Oncology 32(3): 50



The purpose of the study was to explore the diagnostic performance of acoustic radiation force impulse (ARFI) elastography in differential diagnosis between benign and malignant thyroid nodules in patients with coexistent Hashimoto's thyroiditis (HT). A total of 141 pathological proven nodules in 141 HT patients (7 males and 134 females, mean age 50.1 years, range 23-75 years) received conventional ultrasound (US), elasticity imaging (EI) and ARFI elastography, including virtual touch tissue imaging (VTI) and virtual touch tissue quantification (VTQ), before surgery. Shear wave velocity (SWV) and SWV ratio were measured for each nodule on VTQ. The US, EI and ARFI elastography features were compared between benign and malignant nodules in HT patients. Receiver operating characteristic curve (ROC) analyses and area under curve (AUC) were performed to assess the diagnostic performance. Pathologically, 70 nodules were benign and 71 nodules were malignant. Significant differences were found between benign and malignant nodules in HT patients for EI (EI score) and ARFI (VTI grade and SWV) (all P value <0.05). The AUCs for EI, VTI, SWV and SWV ratio were 0.68 [95% confidence interval (CI): 0.59-0.77], 0.90 (95% CI: 0.84-0.95), 0.77 (95%CI: 0.70-0.85) and 0.74 (95%CI: 0.66-0.82), respectively. The cut-off points were EI score ≥3, VTI grade ≥4, SWV ≥2.58 m/s and SWV ratio ≥1.03, respectively. In conclusion, ARFI elastography is useful for differentiation between benign and malignant thyroid nodules in HT patients. The diagnostic performance of ARFI elastography is better than EI.

Please choose payment method:






(PDF emailed within 0-6 h: $19.90)

Accession: 057124708

Download citation: RISBibTeXText

PMID: 25636511

DOI: 10.1007/s12032-015-0502-5


Related references

Comparison of Acoustic Radiation Force Impulse Imaging and Strain Elastography in Differentiating Malignant From Benign Thyroid Nodules. Journal of Ultrasound in Medicine 36(12): 2533-2543, 2017

Differentiation of benign from malignant thyroid nodules with acoustic radiation force impulse technique. British Journal of Radiology 87(1035): 20130263, 2014

Virtual touch tissue imaging on acoustic radiation force impulse elastography: a new technique for differential diagnosis between benign and malignant thyroid nodules. Journal of Ultrasound in Medicine 33(4): 585-595, 2014

Diagnostic Value of Acoustic Radiation Force Impulse Quantification in the Differentiation of Benign and Malignant Thyroid Nodules. Ultrasonic Imaging 39(5): 326-336, 2017

Quantitative Shear Wave Velocity Measurement on Acoustic Radiation Force Impulse Elastography for Differential Diagnosis between Benign and Malignant Thyroid Nodules: A Meta-analysis. Ultrasound in Medicine and Biology 41(12): 3035-3043, 2015

Acoustic radiation force impulse imaging (ARFI) for differentiation of benign and malignant thyroid nodules--A meta-analysis. European Journal of Radiology 84(11): 2181-2186, 2015

Acoustic radiation force impulse elastography for differentiation of malignant and benign breast lesions: a meta-analysis. International Journal of Clinical and Experimental Medicine 8(4): 4753-4761, 2015

Elastography by acoustic radiation force impulse technology for differentiation of benign and malignant breast lesions: a meta-analysis. Journal of Medical Ultrasonics 43(1): 47-55, 2016

Acoustic Radiation Force Impulse (ARFI) imaging for the distinction between benign and malignant thyroid nodules. La Radiologia Medica 120(6): 579-583, 2015

Differentiation of benign and malignant focal liver lesions: value of virtual touch tissue quantification of acoustic radiation force impulse elastography. Medical Oncology 32(3): 68, 2015

Acoustic radiation force impulse induced strain elastography and point shear wave elastography for evaluation of thyroid nodules. International Journal of Clinical and Experimental Medicine 8(7): 10956-10963, 2015

Preliminary study on the diagnostic value of acoustic radiation force impulse technology for differentiating between benign and malignant thyroid nodules. Journal of Ultrasound in Medicine 31(5): 763-771, 2012

Acoustic Radiation Force Impulse Elastography in the Diagnosis of Thyroid Nodules: Useful or Not Useful?. Ultrasound in Medicine and Biology 41(10): 2581-2593, 2015

Acoustic Radiation Force Impulse Quantification in the Evaluation of Thyroid Elasticity in Pediatric Patients With Hashimoto Thyroiditis. Journal of Ultrasound in Medicine 37(5): 1143-1149, 2018

Solid hypo-echoic thyroid nodules on ultrasound: the diagnostic value of acoustic radiation force impulse elastography. Ultrasound in Medicine and Biology 40(9): 2020-2030, 2014